摘要
目的:探讨胎儿颈项透明层(NT)厚度在早孕期胎儿畸形筛查中的价值。方法:对行孕期检查及分娩的2 306例孕妇,孕11～13+6周行彩色多普勒超声检查,系统观察胎儿解剖结构,并测量胎儿NT厚度及鼻骨长度。结果:孕期发现胎儿畸形者32例,孕11～13+6周10例,孕13+6周后22例;胎死宫内13例;染色体异常3例;产前未发现异常而新生儿期出现异常者4例。98例孕11～13+6周NT增厚(NT>2.5 mm)胎儿中有5例预后不良(染色体异常2例,胎死腹中2例,膈疝1例),NT值为4.05～6.20 mm;93例正常胎儿的NT值为2.55～3.60 mm。结论:孕11～13+6周经超声可诊断出一部分解剖结构严重畸形的胎儿,NT>3.6 mm的胎儿出现畸形的可能性高。
Objective： To investigate the value of fetal nuchal translucency（NT） thickness in screening early pregnancy fetal malformation.Methods： The fetal anatomical structure,NT thickness and nasal bone length in 2 306 pregnant women in 11 to 13＋ 6 weeks were detected by color doppler ultrasound.Results： Fetal malformation in 32 cases were found during pregnancy,which included 10 cases in 11 to 13＋ 6 weeks of pregnancy and 22 cases in 13＋ 6 weeks after pregnancy.Fetal death in 13 cases,chromosomal abnormality in 3 cases and abnormal neonate in 4 cases were found.Five fetuses in 98 cases with thickening NT（more than 2.5 mm） during 11 to 13＋ 6 weeks of pregnancy were poor prognosis,which included chromosomal abnormality in 2 case,womb death in 2 cases and diaphragmatic hernia in 1 case,their fetal NT value was 4.05 to 6.20 mm.The normal fetal NT value was 2.55 to 3.60 mm.Conclusions： The ultrasound can diagnose some seriously fetuses malformation in 11 to 13＋ 6 weeks of pregnancy.There is high possibility malformation in fetus with NT value more than 3.6 mm.
出处
《蚌埠医学院学报》
CAS
2013年第8期1031-1033,共3页
Journal of Bengbu Medical College
关键词
产前诊断
胎儿颈项透明层
早孕期
胎儿
出生缺陷
prenatal diagnosis
nuchal translucency
early pregnancy
fetus
birth defect
