摘要
目的:探讨在孕早期(孕12周以前)联合妊娠黄体平均直径和孕囊平均直径与胚芽最大长度之间的差值,对不同年龄孕早期妇女妊娠结局的预测价值。方法:选择采用经阴道彩色多普勒检查313例孕早期的妇女,按年龄分为17～29岁组(184例)、30～39岁组(96例)和≥40岁组(33例),并将各组中满足妊娠黄体平均直径≤1.5cm且孕囊平均直径和胚芽最大长度之间的差值≥1.8cm的归为A组;其余的归为B组,对不同年龄组中A组和B组孕妇胚胎存活和凋亡的情况进行分析。结果:313例孕妇中A组总的胚胎凋亡率(50.00%)高于B组(3.80%),差异有统计学意义(χ2=90.30,P<0.001);3个年龄组中分别对A组和B组的胚胎凋亡情况比较,差异均有统计学意义(χ2=38.99;χ2=32.69;χ2=15.35,P<0.001)。313例中B组共10例发生胚胎凋亡,其中妊娠黄体直径介于1.6～1.7cm或孕囊平均直径和胚芽最大长度之间的差值介于1.5～1.7cm出现胚胎凋亡达6例。结论:妊娠黄体平均直径≤1.5cm且孕囊平均直径和胚芽最大长度之间的差值≥1.8cm可作为判别胚胎凋亡风险的指标临界值,有重要的预测价值;妊娠黄体直径介于1.6～1.7cm或孕囊平均直径和胚芽最大长度之间的差值介于1.5～1.7cm时,有出现胚胎凋亡的风险,临床上应高度警惕并根据病情给予及时治疗。
Objective：To investigate the predictive value of using mean diameter of corpus luteum combi- ning with the difference of GS and embryo for the pregnant outcomes in early pregnant women in different a- ges. Methods：313 early pregnant women were checked through TVS in early pregnancy,whom were divided into three groups according to their age：184 cases in the first group who aged from 17 to 29 years,96 cases in the second group who aged from 30 to 39, and 33 cases in the third group who aged above 40 years. In each group,the women with mean diameter of corpus luteum 〈~ 1.5 cm meanwhile the difference of GS mean diameter and the longest diameter of embryo1〉1.8 cm were classified an class A,the other women were in class B. The differences of pregnant outcome between class A and B in 3 age groups were analyzed. Re- suits：In all 313 cases, embryo mortality of class A was 50. 00% which was significantly higher than that of class B （3.80%） （X 2 =90. 30, P 〈0. 001 ）. The differences on embryo mortality between class A and class B in all the three age groups were significant （X2 =38.99,X2 =32. 69,X2 =15.35,respectively,P〈O. 001 ）. In class B,there were 10 cases with dead ending,among which there were 6 cases dead with mean diameter of corpus luteum between 1.6 ~ 1.7 cm or the difference of GS and Embryo was 1.5 ~ 1.7 cm. Conclusions： Mean diameter of corpus luteum ~〈 1.5 cm and the difference between GS mean diameter and the longest di- ameter of embryo_〉l. 8 cm could be regarded as an critical indicator,which is important to the prediction of embryo mortality. Mean diameter of corpus luteum was between 1.6 -1.7 cm or the difference between GS mean diameter and the longest diameter of embryo was between 1.5- 1.7 cm is a predictive indicator for the risk of embryo dying which should be vigilant about ,and the patients need to be treated properly without delay.
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2013年第8期595-598,共4页
Journal of Practical Obstetrics and Gynecology
关键词
孕早期
黄体
孕囊
胚芽
妊娠结局
Early pregnancy
Corpus luteum
Gestational sac
Embryo
Pregnant outcome
