摘要
目的:探索2型糖尿病患者血脂及脂蛋白与血管病变的相关性。方法:分析120例2型糖尿病患者(59例无血管病变,61例有血管病变)和100例正常人的血脂及脂蛋白。结果:2型糖尿病患者血清TG、TC、LDL-C和ApoB较正常人水平高(P<0.01);而HDL-C、ApoA低于正常人(P<0.01)。有血管病变糖尿病患者TG、TC、LDL-C、ApoB水平高于无血管病变糖尿病患者(P<0.01),HDL-C、ApoA1低于无血管病变患者(P<0.01)。结论:2型糖尿病患者血脂及脂蛋白代谢紊乱,这与血管病变密切相关。
Objective： To explore the relationship between vascular disease and the changes of blood lipid and lipoprotein in type 2 diabetes mellitus patients. Methods： Analyzing blood samples from 120 patients with type 2 diabetes mellitus, including 59 cases suffered from vascular lesions and 6i cases without vascular lesions, and another 100 blood sample from normal subjects. Results： Pa-tients with type 2 diabetes mellitus had higher levels of serum lipid than the normal subjects group, such as TG, TC, LDL-C and ApoB （P〈0.01）, but HDL-C and ApoA1 were lower than the nor-mal subjects （P〈0.01）. The same result was observed in the patients who suffered from vascular le-sions in comparison with the ones without vascular lesions （P〈0. 01）. Conclusion： Protein and lipid me-tabolism disorder in patients with type 2 diabetes, which is associated with vascular disease.
出处
《华夏医学》
CAS
2013年第4期754-756,共3页
Acta Medicinae Sinica
关键词
2型糖尿病
血管病变
血脂
载脂蛋白A
Type 2 diabetes mellitus
vascular disease
apolipoprotein A1
