摘要
T1DM是遗传易感个体在环境因素触发下,由T淋巴细胞介导的以胰岛β细胞选择性破坏为特征的器官特异性自身免疫性疾病。近年来,T1DM在基础和临床研究领域都有了新进展。本文围绕2012年在加拿大维多利亚市召开的第12届国际自身免疫糖尿病会议(IDS)内容,从发病机制、免疫标志物检测新技术、预防治疗临床研究、动物模型等方面对T1DM的全球研究进展和热点作简要评述。
T1DM is an organ-specific autoimmune disease resulting from T cell-mediated destruction of insulin-producing pancreatic D-cells. In recent years, progress in both fundamental and clinical researches marked by a serious of new breakthroughs in the treatment of TIDM has been achieved. This review will focus on the global progress and hotspots of TIDM around the 12th International Conference on the Immunology of Diabetes Society （IDS） from the aspects including pathogenesis, immunological indicators detection, clinical research of prevention and treatment and animal models, in the hope of offering information and thoughts.
出处
《中国糖尿病杂志》
CAS
CSCD
北大核心
2013年第8期762-766,共5页
Chinese Journal of Diabetes
