摘要
目的:建立清热解毒口服液生产工艺的综合评价模式,并应用于该制剂的生产监控。方法:选择清热解毒口服液为研究对象,以共有峰为多变量,采用主成分分析、因子分析等方法实现对数据的压缩、解释,通过少量主分量分析揭示制剂整体质量的变化。结果:最佳提取工艺为加10倍量水提取2次,每次100 min。结论:降维分析法能简化分析过程,且能深刻揭示原始数据的内在规律,适用于对中药整体质量的控制。
Objective： To Establish comprehensive evaluation model of production process of Qingre Jiedu oral liquid, and apply to production monitoring of this preparation. Method： Qingre Jiedu oral liquid was selected as study object, with shared peaks as multivariate variables, principal component analysis, factor analysis and other methods were adopted to achieve data compression and interpretation, and the overall quality changes of preparations was revealed by a small amount of principle component analysis. Result： Optimum extraction technology of Qingre Jiedu oral liquid was： extracted 2 times with 10 times the amount of water, 100 min per time. Conclusion： Dimensionality reduction analysis could simplify analysis process and reveal inherent laws of raw data penetratingly, it was suitable for control of the overall quality of traditional Chinese medicine.
出处
《中国实验方剂学杂志》
CAS
北大核心
2013年第16期18-21,共4页
Chinese Journal of Experimental Traditional Medical Formulae
基金
济南军区后勤科研计划(CJN10L067)
关键词
清热解毒口服液
主成分分析法
因子分析
综合评价
质量控制
Qingre Jiedu oral liquid
principal component analysis
factor analysis
synthesisevaluation
quality control
