摘要
目的调查广东地区育龄妇女TORCH-IgM感染情况及不同季节分布情况,为本地区预防TORCH-IgM提供临床依据。方法收集2011年1月~2012年12月育龄妇女筛查血样,采用ELISA方法对TORCH-IgM抗体进行检测,450nm波长读取吸光度,以Cut-off值和ISR值判断结果。结果广东地区育龄妇女TORCH-IgM阳性率从高到低分别是HSV-IgM3.97%、TOX-IgM 1.32%、RV-IgM 1.90%、CMV-IgM 0.74%;适龄妇女RV-IgM、CMV-IgM、HSV-IgM阳性率分别为2.05%、0.78%、4.42%,高于高危妇女的1.33%、0.58%、2.26%;而高危妇女TOX-IgM阳性率(2.19%)高于适龄妇女的阳性率(1.18%),两者进行比较,差异有统计学意义(P<0.05);不同季节育龄妇女TORCH-IgM感染明显不同,夏季TORCH-IgM感染明显高于春、秋、冬季。结论加强对育龄妇女进行TORCH-IgM孕前筛查宣传工作,控制TORCH-IgM感染以预防为主,做到早诊断、早治疗。
Objective To investigation the infection status of TORCH-IgM and the distribution in different seasons in women of child-bearing age in Guangdong area,in order to provide guidance for prevention on TORCH infection.Methods The serum samples of women of child-bearing age were collected from January 2011 to December 2012.The serum samples were tested for TORCH-IgM antiboby by ELISA.The absorbance of 450 nm wavelength was taken,according to the cut-off value and ISR value to analyze the result.Results The positive rate of TORCH-IgM in women of childbearing age in Guangdong area from high to low were HSV-IgM(3.97%),TOX-IgM(1.32%),RV-IgM(1.90%),and CMV-IgM(0.74%).The positive rates of RV-IgM,CMV-IgM,and HSV-IgM in women of maternal age were 2.05%,0.78%,and 4.42%,respectively,higher than those in women of advanced maternal age(1.33%,0.58%,and 2.26%,respectively).And the positive rate of TOX-IgM in women of advanced maternal age(2.19%) was higher than that in women of maternal age(1.18%),and the difference was statistically significant(P0.05).The TORCH-IgM infection in different seasons of women of childbearing age was significantly different,and the infection of TORCH-IgM in summer was significantly higher than that in spring,autumn and winter.Conclusion We should strengthen propaganda work on TORCH-IgM screening before pregnancy,and control the TORCH-IgM infection based on prevention,in order to early diagnosis and early treatment.
出处
《国际检验医学杂志》
CAS
2013年第14期1835-1837,共3页
International Journal of Laboratory Medicine