期刊文献+

广东地区育龄妇女TORCH-IgM感染情况调查分析 被引量:7

Investigation on TORCH-IgM infection in women of childbearing age in Guangdong area
下载PDF
导出
摘要 目的调查广东地区育龄妇女TORCH-IgM感染情况及不同季节分布情况,为本地区预防TORCH-IgM提供临床依据。方法收集2011年1月~2012年12月育龄妇女筛查血样,采用ELISA方法对TORCH-IgM抗体进行检测,450nm波长读取吸光度,以Cut-off值和ISR值判断结果。结果广东地区育龄妇女TORCH-IgM阳性率从高到低分别是HSV-IgM3.97%、TOX-IgM 1.32%、RV-IgM 1.90%、CMV-IgM 0.74%;适龄妇女RV-IgM、CMV-IgM、HSV-IgM阳性率分别为2.05%、0.78%、4.42%,高于高危妇女的1.33%、0.58%、2.26%;而高危妇女TOX-IgM阳性率(2.19%)高于适龄妇女的阳性率(1.18%),两者进行比较,差异有统计学意义(P<0.05);不同季节育龄妇女TORCH-IgM感染明显不同,夏季TORCH-IgM感染明显高于春、秋、冬季。结论加强对育龄妇女进行TORCH-IgM孕前筛查宣传工作,控制TORCH-IgM感染以预防为主,做到早诊断、早治疗。 Objective To investigation the infection status of TORCH-IgM and the distribution in different seasons in women of child-bearing age in Guangdong area,in order to provide guidance for prevention on TORCH infection.Methods The serum samples of women of child-bearing age were collected from January 2011 to December 2012.The serum samples were tested for TORCH-IgM antiboby by ELISA.The absorbance of 450 nm wavelength was taken,according to the cut-off value and ISR value to analyze the result.Results The positive rate of TORCH-IgM in women of childbearing age in Guangdong area from high to low were HSV-IgM(3.97%),TOX-IgM(1.32%),RV-IgM(1.90%),and CMV-IgM(0.74%).The positive rates of RV-IgM,CMV-IgM,and HSV-IgM in women of maternal age were 2.05%,0.78%,and 4.42%,respectively,higher than those in women of advanced maternal age(1.33%,0.58%,and 2.26%,respectively).And the positive rate of TOX-IgM in women of advanced maternal age(2.19%) was higher than that in women of maternal age(1.18%),and the difference was statistically significant(P0.05).The TORCH-IgM infection in different seasons of women of childbearing age was significantly different,and the infection of TORCH-IgM in summer was significantly higher than that in spring,autumn and winter.Conclusion We should strengthen propaganda work on TORCH-IgM screening before pregnancy,and control the TORCH-IgM infection based on prevention,in order to early diagnosis and early treatment.
出处 《国际检验医学杂志》 CAS 2013年第14期1835-1837,共3页 International Journal of Laboratory Medicine
关键词 妊娠并发症 感染性 免疫球蛋白M 风疹病毒 弓形虫属 疱疹病毒2型 巨细胞病毒感染 pregnancy complications infectious immunoglobulin M rubella virus toxoplasma herpesvirus 2 human cytomegalovirus infections
  • 相关文献

参考文献9

二级参考文献57

共引文献104

同被引文献76

  • 1张宁,闫素文,封志纯.妊娠期ToRCH 筛查指南[J].发育医学电子杂志,2013,1(4):236-256. 被引量:10
  • 2周希亚,刘俊涛.TORCH宫内感染及其产前诊断[J].中国产前诊断杂志(电子版),2009,1(2):4-6. 被引量:7
  • 3刘瑾,顾晓慧,叶国玲,赵晓岚,张磊,邬晋芳,蔡小宁,刘琦.孕妇TORCH感染与胎儿畸形的关系[J].第四军医大学学报,2004,25(18):1682-1685. 被引量:20
  • 4国家人口和计划生育委员会关于开展出生缺陷一级预防工作的指导意见[J].中国计划生育学杂志,2007,15(11):653-657. 被引量:28
  • 5Cutts FT, Best J, Siqueira MM, et al. Guidelines for surveillance ofcongenital rubella syndrome and rubella [ EB/OL ]. WHO/V&B/99.22. Geneva : World Health Organization, May 1999. http ://whqlibdoc.who. int/hq/1999/WHO_V&B_99.22. pdf. 被引量:1
  • 6Adam 0, Ali AK,Htibschen JM,et al. Identification of congenital ru-bella syndrome in Sudan[ J] . BMC Infect Dis,2014,14:305. 被引量:1
  • 7World Health Organization. Rubella and congenital rubella syndromecontrol and elimination-global progress, 2012 [ J ]. Wkly EpidemiolRec,2013,88 (49 ):521-532. 被引量:1
  • 8N. Shetty,J. W. Tang,J. Andrews,主编.感染性疾病-病因、预防及案例研究[M].郑明华,主译.北京:人民卫生出版社,2011:134-155. 被引量:1
  • 9国家人口计生委.国家人口计生委关于印发国家免费孕前优生健康检查项目试点工作技术服务规范(试行)的通知(国人口发[2010]31号)[S/OL].(2010-05-15)[2015-04-08]http://www.moh.gov.cn/fys/s3589/201307/4bad01a08a07468e87b583b28f082d53.shtml. 被引量:1
  • 10国家食品药品监督管理总局.关于发布体外诊断试剂临床试验技术指导原则的通告(国家食品药品监督管理总局2014年第16号通)[S/OL].(2014-09-11)[2015-04-08].http://www.sfda.gov.cn/WS01/CL0087/106241.html. 被引量:1

引证文献7

二级引证文献27

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部