摘要
基底动脉闭塞病情重,致死率和致残率高,静脉溶栓、动脉溶栓治疗和机械取栓治疗是目前最常见的治疗方法。与静脉溶栓相比,动脉溶栓或机械取栓治疗血管再通率较高,且时间窗较静脉溶栓治疗宽,但目前的研究并未证实动脉溶栓或机械取栓治疗优于静脉溶栓治疗。桥接治疗是结合静脉溶栓与动脉溶栓或机械取栓的具有发展前景的一种治疗新模式,但其有效性还需要进一步证实。本文将对急性基底动脉闭塞相关的治疗方法:静脉溶栓、动脉溶栓、机械取栓治疗等做一综述,以促进对急性基底动脉闭塞血管再通治疗的认识。
Acute basilar artery occlusion （BAO） is a devastating neurological condition with a high rate of fatality and disability. Compared with intravenous thrombolysis （IVT）, the recanalization of intraarterial thrombolysis （IAT） or mechanical thrombectomy is higher and the thrombolysis treatment time is longer, but it is not confirmed in reported researches that IAT or mechanical thrombectomy is better than IVT. The bridging therapy which combines IVT with IAT or mechanical thrombectomy therapy is a new treatment mode, but its effectiveness needs to be confirmed. We reviewed the different thrombolysis therapies to further understand the treatment progress of BAO which include IVT, IAT, mechanical thrombectomy and so on.
出处
《中国卒中杂志》
2013年第7期580-584,共5页
Chinese Journal of Stroke
关键词
基底动脉闭塞
溶栓
机械取栓
桥接治疗
Basilar occlusion
Thrombolysis
Mechanical thrombectomy
Bridging therapy
