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3种给药方案治疗细菌性阴道炎的成本-效果分析 被引量:5

Cost-effectiveness Analysis of 3 Kinds of Therapeutic Regimes in the Treatment of Bacterial Vaginitis
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摘要 目的:探讨治疗细菌性阴道炎3种给药方案的经济学效果。方法:按用药情况不同,将188例我院妇科门诊收治的细菌性阴道炎患者分为A、B、C组。于月经结束3d后,每晚用水清洗外阴后,A、B、C组患者分别给予硝呋太尔制霉素阴道软胶囊1粒、甲硝唑呋喃唑酮栓1粒、甲硝唑栓1粒,置于阴道后穹窿,分别以6、5、7d为1个疗程。均于停药7d后到门诊妇科复查,观察各组患者的疗效和不良反应,并进行成本-效果分析。结果:A、B、C组成本分别为179.35、156.70、136.66元,总有效率分别为96.92%、88.52%、82.26%,成本-效果比分别为185.05、177.02、166.13,A、B组相对于C组的增量成本-效果比分别为291.20、320.13。结论:硝呋太尔制霉素阴道软胶囊治疗细菌性阴道炎效果较佳。 OBJECTIVE:To explore the pharmacoeconomic effectiveness of 3 kinds of therapeutic regimes for bacterial vaginitis.METHODS:188 patients with bacterial vaginitis were divided into 3 groups according to drug use.3 days after menstruation,after vulva was cleaned with water every night,group A,B and C were given a piece of Nifuratel nysfungin vaginal soft capsules,Metronidazole furazolidone suppositories and Metronidazole suppositories into vaginal posterior fornix.A treatment course of them lasted for 6,5 and 7 days.They went to outpatient department to recheck 7 days after drug withdrawal;therapeutic efficacy and ADR were observed and cost-effectiveness was analyzed.RESULTS:The costs of 3 groups were 179.35,156.70 and 136.66 yuan,respectively;total effective rates were 96.92%,88.52% and 82.26%,respectively;the cost-effectiveness ratios were 185.05,177.02 and 166.13,respectively.Compared with group C,the incremental cost-effectiveness ratio of group A and B were 291.20 and 320.13.CONCLUSIONS:Nifuratel nysfungin vaginal soft capsules is a better regimen for bacterial vaginitis.
作者 林晶 李虹
出处 《中国药房》 CAS CSCD 2013年第30期2785-2787,共3页 China Pharmacy
关键词 细菌性阴道炎 治疗方案 成本-效果分析 Bacterial vaginitis Therapeutic regimes Cost-effectiveness analysis
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