摘要
目的:探讨多囊卵巢综合征不孕症的临床治疗方法,以及使用该方法对妊娠结果的影响情况。方法:对笔者所在医院2010年1月-2011年1月这一年间,69例多囊卵巢综合征不孕症患者进行治疗,以恢复生育的为目的,方案采用二甲双胍与克罗米芬联合治疗,疗程为12周,对比治疗前后LH(促黄体生成素)、T(睾酮)、FINS(空腹检测胰岛素水平)和FBG(空腹血糖值)的水平变化,以及最终妊娠的情况。结果:治疗后T、LH与FINS的含量比治疗前下降较显著,差异有统计学意义(P<0.05),FBG的水平在治疗前后比较差异无统计学意义(P>0.05),经过治疗后,42例(60.87%)有排卵现象,最终合计有29例(42.03%)成功妊娠。结论:采用二甲双胍与克罗米芬联合治疗多囊卵巢综合征不孕症的临床效果较好,排卵率达60.87%,且增加了妊娠的几率,无副作用,较安全。
Objective： To explore the methods of polycystic ovary syndrome infertility card, and the influence of the results.Methods： In our hospital from January 2010 to January 2011 69 cases of infertility patients with polycystic ovary syndrome treatment, the purpose in the treatment of the disease was restore fertility, scheme mefformin plus clomiphene citrate combination therapy, period of treatment for 12 weeks, compared to before and after treatment LH（luteinizing）, T（testosterone）, FINS（fasting detection insulin levels） and FBG（fasting blood sugar value） level changes, and finally the pregnancy.Results： After treatment, T, LH and the content of FINS than before treatment down more, there was statistical significant（P〈O.05）, FBG level before and after treatment was nosignificantdifferenee（P〉0.05）, after treatment , and patients （60.87%） with oviposit phenomenon, finally had a tota129 patients（42.03%） successful pregnancy. Conclusion： Mefformin and clomiphene citrate combination therapy polycystic ovary syndrome infertility syndrome of clinical effect is better, ovulation rate is high, and it increases the risk of pregnancy, no side effect, it is safer.
出处
《中外医学研究》
2013年第21期13-14,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
多囊卵巢综合征
不孕症
二甲双胍
克罗米芬
Polycystic ovary syndrome
Infertility
Mefformin
Clomiphene citrate
