期刊文献+

急性冠状动脉综合征调脂治疗 被引量:2

原文传递
导出
摘要 急性冠状动脉综合征(ACS)患者特别是急性心肌梗死(AMI)患者,可因应激状态,基线血脂浓度有较大波动。AMI发生24h后,总胆固醇(TC)、低密度脂蛋白胆固醇(LDL—C)、高密度脂蛋白胆固醇(HDL—C)、载脂蛋白(apo)AI及apoB均有明显下降,而甘油三酯(TG)却增加;4—5d后变化最为明显,2~3个月后可回到基线状态。此外,LDL和HDL颗粒的性质也会发生变化。目前认为,对于ACS患者,无论基线血脂浓度如何,都需要积极地应用他汀类药物,进行强化降脂治疗。
作者 赵水平
出处 《中华心血管病杂志》 CAS CSCD 北大核心 2013年第7期542-543,共2页 Chinese Journal of Cardiology
  • 相关文献

参考文献8

  • 1Spencer FA,Allegrone J,Goldberg RJ, et al. Association of statintherapy with outcomes of acute coronary syndrome : The GRACEstudy. Ann Intern Med, 2004,140:857-866. 被引量:1
  • 2Fonarow GC,Wright RS,Spencer FA,et al. Effect of statin usewithin the first 24 hours of admission for acute myocardialinfarction on early morbidity and mortality. Am J Cardiol,2005,96:611-616. 被引量:1
  • 3Schwartz GG,Olsson AG,Ezekowitz MD,et al. Effects ofatorvastain on early recurrent ischemic events in acute coronarysyndromes : the MIRACLE study : arandomized controlled trial.JAMA, 2001,285 :1711-1718. 被引量:1
  • 4Cannon CP, Braunwald E, McCabe C, et al. Intensive versusmoderate lipid lowering with statins after acute coronarysyndromes. N Engl J Med, 2004,350: 1495-504. 被引量:1
  • 5de Lemos JA,Blazing MA,Wiviott SD, et al. Early intensive vs adelayed conservative simvastatin strategy in patients with acutecoronary syndromes : phase Z of the A to Z trial. JAMA,2004,292:1307-1316. 被引量:1
  • 6Briel M,Schwartz GG,Thompson PL,et al. Effects of earlytreatment with statins on short-term clinical outcomes in acutecoronary syndromes : a meta-analysis of randomized controlledtrials. JAMA,2006,295:2046-2056. 被引量:1
  • 7Grundy SM,Cleeman JI,Merz CN,et al. Implications of recentclinical trials for the national cholesterol education program adulttreatment panel HI guidelines. Circulation,2004,110 :227-239. 被引量:1
  • 8European Association for Cardiovascular Prevention andRehabilitation, Reiner Z, Catapano AL, et al. ESC/EASGuidelines for the management of dyslipidaemias : the Task Forcefor the management of dyslipidaemias of the European Society ofCardiology ( ESC ) and the European Atherosclerosis Society(EAS). Eur Heart J, 2011,32:1769-1818. 被引量:1

同被引文献26

引证文献2

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部