摘要
目的观察在白内障术后联合应用抗生素滴眼液与非甾体类抗炎药滴眼液,探讨在白内障超乳术后联合应用抗生素滴眼液与非甾体类抗炎药的安全性与有效性。方法随机选择无并发症的白内障患者180例(180只眼),随机分为3组,每组60只眼,施行白内障超声乳化吸除联合人工晶体植入术。A组:术后单独使用妥布霉素地塞米松滴眼液;B组:术后联合使用妥布霉素地塞米松滴眼液与普拉洛芬滴眼液;C组:术后联合使用加替沙星滴眼液与普拉洛芬滴眼液。分别于术后第3天,7天和14天测量眼压。各指标均采用均数±标准差(χ—±s)表示,组间均数比较采用单因素方差分析,组间的多重比较采用q检验法,以P<0.05有统计学意义。结果术后A组与B组眼压测定值均较C组明显增高(P<0.01),B组眼压测定值较A组降低(P<0.05)。结论加替沙星滴眼液与普拉洛芬滴眼液联合使用具有安全性高的特点,可用于白内障超声乳化术后的患者。
Objective To investigate the effects of combined with antibiotic eye drops and non-steroidal anti-inflammatory drugs eye drops after cataract surgery, then further study its safety and effectiveness after phacoemulsification. Methods One hundred and eighty cataract patients without complications were divided into three groups randomly： A group： used tobramycin dexamethasone eye drops after phacoemulsification. B group： used tobramycin dexamethasone eye drops and pranoprofen eye drops after phacoemulsification. C group： used gatifloxacin eye drops and pranoprofen eye drops after phacoemulsification. Then measured intraocular pressure at 3 days, 7days and 14 days after phacoemulsification. The results were showed by means plus or subtracting standard, the groups means was compared by one-way aonva, the deviation of between groups means was compared by Student-Newman-Keuls. The difference of P〈0.05 had statistical significance. Results The intraocular pressure was significantly elevated in A group and B group compared with C group （P〈0.01）. The intraocular pressure was significantly reduced in B group compared with A group at 3 days, 7days and 14 days after phacoemulsification （P〈0.05）. Conclusion To combine with gatifloxacin eye drops and pranoprofen eye drops was safety and effectiveness. It may be used to treat cataract patients after phacoemulsification.
出处
《中国医药指南》
2013年第17期32-33,共2页
Guide of China Medicine
