摘要
目的观察瑞舒伐他汀钙对脑梗死患者的动脉粥样硬化及脑血流动力学的影响。方法对68例脑梗死患者应用瑞舒伐他汀钙10 mg/d连续口服6个月,观察治疗前后颈内动脉粥样硬化程度、狭窄程度、不稳定斑块及双侧大脑中动脉的血流情况。结果经治疗6个月后,患者不稳定斑块检出率下降,颈内动脉粥样硬化程度、狭窄程度及双侧大脑中动脉的血流情况均较前改善,且治疗前后比较均有显著性差异(P均<0.05)。结论对于脑梗死患者,瑞舒伐他汀钙有稳定及逆转动脉斑块的作用,具有显著抗动脉粥样硬化和改善脑血流动力学的作用,可以在缺血性脑卒中临床二级预防中广泛应用。
Objective It is to observe the influence of Rosuvastatin on atherosclerosis and cerebral hemodynamics in patients with acute cerebral infarction.Methods 68 patients with acute cerebral infarction received Rosuvastatin treatment 10 mg every day for 6 months.The changes of carotid atherosclerosis,carotid artery stenosis,unstable plaque and cerebral hemodynamics were observed after treatment.Results After treatment for 6 months,the detectable rate of unstable plaques was lower,the degree of carotid atherosclerosis and carotid artery stenosis and the situation of cerebral hemodynamics were improved,there were significant differences compared with before treatment（P 0.05）.Conclusion Rosuvastatin can make the plaque stable and reversal,has significant anti-artery atherosclerosis effect and improves cerebral hemodynamics in patients with cerebral infarction.So it can be used generally in the secondary prevention of cerebral ischemic stroke.
出处
《现代中西医结合杂志》
CAS
2013年第20期2178-2180,共3页
Modern Journal of Integrated Traditional Chinese and Western Medicine
