摘要
以聚醚醚酮/钡玻璃粉(PEEK-BGF)复合材料为基体,通过硅烷偶联剂,在复合材料表面构建具有生物活性的纳米羟基磷灰石(nHA)和甲基丙烯酸酯基的光固化树脂复合涂层.采用扫描电子显微镜(SEM)和X射线光电子能谱(XPS)分析了材料表面形貌和元素分布,测试了涂层与复合材料之间的粘接强度.通过检测大鼠成骨细胞总蛋白含量和碱性磷酸酶表达水平,评价新型光固化纳米羟基磷灰石/聚甲基丙烯酸酯(nHA/PMMA)复合涂层的生物活性.研究结果表明,nHA填充的光固化复合材料形成粗糙的表面,随着nHA的填充量提高,涂层表面生物学活性得到提高.
By the linkage of silane coupling agent, light cured coating was formed on poly（ether ether ketone）/barium-containing glass filler（PEEK-BGF） composite surface. The coating was composed of bioactive nano hydroxyapatite（nHA） and methacrylate light cure resin. Scanning electron microscope（SEM） and X-ray photoelectron spectroscopy（XPS） were used to analyze the topography and elements distribution feature of the sample surface, and the bonding strength was tested by the universal testing machine. Rat osteoblasts cells were cultured on the material surface. The total protein concentration test and alkaline phosphatase（ALP） assay of osteoblasts were performed to examine the bioactivity of new type light cured nano hydroxyapatite/polymethacrylate（nHA/PMMA）hybrid coating. The results show that the nHA hybrid coating can form a rough morphology on the composite surface. With the increase of nHA content, the bioactivity of the coating is enhanced.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
2013年第7期1782-1787,共6页
Chemical Journal of Chinese Universities
基金
吉林省科技发展规划项目(批准号:20106020)资助
关键词
聚醚醚酮
复合材料
生物活性
光固化涂层
纳米羟基磷灰石
Poly（ ether ether ketone）
Composite
Bioactivity
Light cured coating
Nano hydroxyapatite
