摘要
目的:探讨不同程度低蛋白血症与结核患者肺部病变性质、范围的相关性。方法:对2006年6月~2008年6月住院治疗,合并低蛋白血症的167例初治肺结核患者,根据治疗前血清白蛋白水平(ALB<35g/L,ALB<30g/L,ALB<25g/L)分为轻、中、重3组,为观察组。并设同期住院治疗的不合并低蛋白血症的初治肺结核患者216例为对照组,观察各组的病变类型、肺部病变范围。结果:血型播散型肺结核患者的血清ALB水平与血型播散型肺结核两者呈负相关(r=-0.958,P=0.042<0.05)。肺部病变范围对照组肺部病变范围>3个肺野者占38.7%;病例组中轻、中、重度低蛋白血症组肺部病变范围>3个肺野者所占比例分别为48.3%、61.9%、85.7%,均高于对照组。4组之间比较有显著差异性(P<0.05)。分析4组患者的血清ALB水平与肺部病变范围的相关性,两者呈负相关(r=-0.284,P=0.000<0.01)。结论:血清白蛋白水平与患者的肺部病变范围呈显著负相关,提示低蛋白血症使患者的肺部病变范围更广泛。
Objective:To study correlation between different hypoproteinemia and lung extent of disease and lesions nature.Methods: According to the serum albumin level of prior treatment ALB35g/L,ALB30g/L,ALB25g/L,167 tuberculous patients with hypoproteinemia, who were hospitalized for initial treatment,were divided into three subgroups:light,middling and severity.These patients were studied as research group.216 pulmonary tuberculosis patients without hypoproteinemia,who were also hospitied during the same periods were selected as control group.Results:Disseminated blood type lung tuberlosis The correlation between the level of ALB and disseminated blood type lung tuberlosis were negative(r = -0.958,P =0.0420.05).The lung extent of tuberlosis In control group,there was 38. 7%patients whose lung extent3 lung fields,and were 48.3%,61.9%,85.7%in light,middling and severity separately.There were significant difference in each of research groups and control group(P0.05 ).The correlation between the level of ALB and the lung extent of tuberlosis were negative(r = - 0.284,P = 0.0000.01).Conclusion:There were significant negative correlation between level of ALB and the lung extent of tuberlosis.This results supposed the lung extent of tuberlosis in hypoproteinemia were more than in control group.
出处
《中国伤残医学》
2013年第6期58-60,共3页
Chinese Journal of Trauma and Disability Medicine
关键词
低蛋白血症
结核
肺部病变
Hypoproteinemia
Tuberculosis
Lung of disearce