摘要
目的:观察心康饮治疗扩张型心肌病利尿剂抵抗的临床疗效。方法:采用质反应开放型单向序贯设计,在西医治疗的基础上给予心康饮口服,疗程两周,观察患者治疗前后每日尿量的改变以及利尿剂用量,依据实验结果绘制序贯实验图。结果:与治疗前比较,治疗后第1天至第7天及第2周平均24 h尿量较治疗前差异有统计学意义(P<0.001)。心康饮治疗后呋塞米用量明显减少,治疗后第3天到第2周与治疗前相比,差异均有统计学意义(P<0.01)。结论:心康饮对改善心肾阳虚、宗气下陷型扩张型心肌病利尿剂抵抗有较显著的疗效,可明显增加患者24 h尿量、减少利尿剂的用量。
Objective： To observe the clinical efficacy of Heart Health Beverage in Treating Diuretic Resistance in Dilated Cardiomyopathy. Methods： The design of quantitative response, open type and one-way sequential trial was applied. Patients were treated by Heart Health Beverage as well as basic treatment of Western medicine; the treatment course was 2 weeks and the daily urinary volume and diuretic dose were observed. The Sequential trial diagram was drawn according the results. Results： The 24 h urine volume at the first day, seventh day and second week increased, with significance difference （P〈0.01）. The dose of Furosemide at the third day to the second week was decreased, with significance difference （P〈0.01）. Conclusion： Heart Health Beverage can provide obvious effect on diuretic resistance in dilated cardiomyopathy, which is identified as ＂ Yang Deficiency of heart and kidney＂ and ＂Ancestral Qi Falling＂, increasing the 24 h urine volume and reducing the diuretic dose.
出处
《中医药导报》
2013年第6期11-13,共3页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
基金
湖南省科技厅项目(2012FJ6020)
关键词
扩张型心肌病
利尿剂抵抗
心康饮
序贯试验
Dilated cardiomyopathy
Diuretic resistance
Heart Health Beverage
Sequential trial
