摘要
目的探讨中老年男性2型糖尿病(T2DM)患者血清尿酸水平与颈动脉粥样硬化的相关性。方法将男性T2DM患者132例,按是否有颈动脉粥样硬化分为颈动脉粥样硬化组(AS组)和非颈动脉粥样硬化组(非AS组),同期选择我院健康体检者男性39例作为健康对照组(NC组),测定尿酸、年龄、病程、体质量指数、血压、空腹血糖、低密度脂蛋白胆固醇、胆固醇、三酰甘油、高密度脂蛋白胆固醇、糖化血红蛋白等指标,并进行多因素Logistic回归分析。结果 AS组尿酸水平高于非AS组、NC组;非AS组尿酸水平高于非AS组。多因素Logistic回归分析表明血清尿酸水平、年龄是中老年男性T2DM患者发生颈动脉粥样硬化的独立相关因素。结论尿酸可能在T2DM患者颈动脉粥样硬化的发生发展中起着重要作用。
Objective To explore the relationship between serum level of uric acid and carotid atherosclerosis in middle-aged and old-aged male patients with type 2 diabetes mellitus（T2DM）. Methods 132 T2DM patients with or without carotid atherosclerosis and 39 normal subjects were enrolled in the study. Serum uric acid and body mass index （ BMI ）, fasting blood glucose （ FBG）, systolic blood pressure （ SBP）, diastolic blood pressure （ DBP）, serum cholesterol （TC） and triglyceride （TG）were analyzed. Results The level of uric acid significantly increased in type 2 diabetes mellitus with carotid atherosclerosis. Logistic regressive analysis showed that the independent risk factor associated with carotid atherosclerosis was uric acid and age. Conclusion The levels of serum uric acid may be associat- ed with the occurrence and development of carotid atheroselerosis in middle aged and old aged male patients with T2DM.
出处
《中国临床保健杂志》
CAS
2013年第3期282-284,共3页
Chinese Journal of Clinical Healthcare
关键词
糖尿病
2型
尿酸
颈动脉疾病
危险因素
Diabetes mellitus, type 2
Uric acid
Carotid artery diseases
Risk factors
