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老年糖尿病合并急性心肌梗死患者糖化血红蛋白与肌酸激酶及其同工酶的相关性研究 被引量:4

Relationship between HbAlc and CK, CK-MB and CK-MB/CK ratio in the elderly diabetes mellitus patients with acute myocardial infarction
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摘要 目的研究老年2型糖尿病(T2DM)合并急性心肌梗死(AMI)患者糖化血红蛋白(HbA1c)与肌酸激酶及其同工酶的相关性。方法根据HbA1c水平,将120例T2DM合并AMI患者分为五组:A组,HbA1c:4.00%-5.99%:B组,HbA1c:6.00%~6.99%:C组,HbA1c:7.00%~7.99%;D组,HbA1c:8.00%-8.99%;E组,HbA1c:≥9.00%。测定每例患者的血清肌酸激酶(CK)、血清肌酸激酶同工酶(CK-MB),计算CK—MB/CK比值。结果五组比较,C组CK—MB/CK比值低于其余四组(P〈0.05)。结论HbA1c在7.00%-7.99%时CK—MB/CK比值最低,提示将HbA1c控制在7.00%-7.99%时老年T2DM合并AMI患者的心肌损伤程度最小。 Objective To investigate the relationship between HbA1 c and CK, CK-MB and CK- MB/CK ratio in the elderly type 2 diabetes (T2DM) patients with acute myocardial infarction (AMI). Methods One hundred and twenty patients were divided into five groups according to the level of HbAlc: group A, HbAlc: 4.00% -5.99% ; group B, HbAlc:6.00% -6.99% ; group C, HbAlc: 7.00%-7.99%; group D, HbAlc: 8.00% -8.99%; group E, HbAle: ≥9.00%. The CK, CKMB were measured in all the cases, and the CK-MB/CK ratio was calculated. Results The CK-MB/CK ratio in group C was lower than the rest of the four groups ( P 〈 0.05 ). Conclusions When HbA1 c controlled in 7.00% - 7.99% , CK-MB/CK ratio is the lowest, so that myocardial damage of the elderly T2DM patients with AMI is the smallest.
出处 《中国实用医刊》 2013年第14期42-44,共3页 Chinese Journal of Practical Medicine
关键词 2型糖尿病 急性心肌梗死 糖化血红蛋白 肌酸激酶 肌酸激酶同工酶 Type 2 diabetes Acute myocardial infarction Haemoglobin A1 c Creatine kinase Creatine kinase-MB
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