摘要
目的体外观察薰衣草精油和芦荟水提物对痤疮患者面部痤疮丙酸杆菌和表皮葡萄球菌的作用,为改善面部痤疮治疗提供理论依据。方法采用连续梯度稀释法稀释薰衣草精油及芦荟水提物,纸片法观察不同浓度的精油和芦荟水提物对面部正常菌群表皮葡萄球菌和痤疮主要致病菌痤疮丙酸杆菌的作用;通过抑菌环的大小反应抑菌作用强弱,测定生长曲线以观察对细菌生长繁殖的影响。结果薰衣草精油对痤疮丙酸杆菌的抑菌作用明显强于表皮葡萄球菌(P<0.05);两种芦荟(库拉索芦荟和木立芦荟)对痤疮丙酸杆菌均无抑菌作用(P>0.05);库拉索芦荟对表皮葡萄球菌有微弱的抑制作用(P<0.05);木立芦荟对表皮葡萄球菌生长有促进作用。结论薰衣草精油和芦荟水提物对痤疮患者面部主要细菌表皮葡萄球菌和痤疮丙酸杆菌的作用效果不同,薰衣草精油和木立芦荟水提物联合应用有可能通过调整面部微生态平衡从而改善痤疮症状。
Objective To provide theoretical proofs for facial acne treatment by observing the influence of lavender essential oil and aqueous extract of aloe on main flora of facial acne（Propionibacterium acnes and Staphylococcus epidermidis） in vitro.Methods Serial dilution method was adopted to dilute lavender essential oil and aquedous extract of aloe.Paper disc method was performed to observe the effects of different concentrations of lavender essential oil and aquedous extract of aloe on facial flora.The effect of bacteriostasis was represented by the area of inhibition zone.Growth curve was plotted to detect the influence on bacteria growth.Results Lavender essential oil showed a stronger inhibitory activity against Propionibacterium acnes than Staphylococcus epidermidis（P0.05）;Aloe vera and aloe arborescens mill did not seem to have inhibitory effect on Propionibacterium acnes（P0.05）;Aloe vera had a weak inhibitory effect on Staphylococcus epidermidis（P0.05）,while Aloe arborescens Mill showed a positive growth-promoting effect on Staphylococcus epidermidis.Conclusion The influences of lavender essential oil and aqueous extract of aloe on main flora of facial acne（Staphylococcus epidermidis and Propionibacterium acnes） are different.Application of lavender essential oil combined with aloe might help to improve facial acne symptoms through modulating facial microecological balance.
出处
《中国微生态学杂志》
CAS
CSCD
2013年第6期656-658,662,共4页
Chinese Journal of Microecology
关键词
薰衣草精油
库拉索芦荟
木立芦荟
痤疮丙酸杆菌
表皮葡萄球菌
Lavender essential oil
Aloe vera
Aloe arborescens Mill
Propionibacterium acnes
Staphylococcus epidermidis
