摘要
目的观察曲美他嗪治疗急性心肌梗死后心律失常的临床疗效及安全性。方法将80例急性心肌梗死后心律失常患者随机分为二组,对照组应用常规治疗,治疗组在对照组的基础上加用盐酸曲美他嗪治疗。观察二组用药前后心律失常发作情况、药物的耐受性及不良反应。结果治疗组与对照组均能减少心律失常发作,但治疗组总有效率为90.0%,高于对照组(70.0%),差异有统计学意义(P<0.05)。结论盐酸曲美他嗪可有效治疗急性心肌梗死后心律失常发作,值得临床推广应用。
Abstract Objective To observe efficacy and safety of trimetazidine on ventricuiar arrhytluma m patients with acute myocardial infarction. Methods Eighty patients with ventricuiar arrhytlunia after acute myocar- dial infarction were randomly divided into two groups, control group received conventional therapy, the treatment group were added trimetazidine on the basis of conventional therapy. Then attack times of ventri- cuiar arrhytlunia and tolerance and adverse reactions of drugs were observed before and after using trimeta- zidine. Results Attack times of ventricuiar arrhytlunia was reduced in both the control group and the treat- ment group, but the total efficiency rate of the treatment group was 90.0%, higher than the control group 70.0%, and with a statistical significance （P〈0.05）. Conclusion Trimetazidine is an efIective drug on treating the patients with ventricuiar arrhytlunia after acute myocardial infarction and it is worthy of clinical application.
出处
《中国煤炭工业医学杂志》
2013年第6期946-948,共3页
Chinese Journal of Coal Industry Medicine
关键词
曲美他嗪
急性心肌梗死
心律失常
能量代谢
疗效
Trimetazidine ~ Acute myocardial infarction
Ventricuiar arrhytlunia~ Energy metabolism~ Efficacy
