摘要
目的:优选健脾颗粒中橙皮苷的提取工艺。方法:以处方中的主要药效成分橙皮苷含量为观察指标,采用正交设计法筛选最佳提取工艺条件。结果:最佳提取方法为回流1.0 h、加95%甲醇50 ml。结论:优选的提取方法为健脾颗粒中橙皮苷含量测定提供可靠方案,保证产品质量。
OBJECTIVE：To optimize the extraction technology of hesperidin in Jianpi granules （granules for strengthening spleen）. METHODS： The extraction technology of hesperidin in Jianpi granulea was optimized using orthogonal design with the main active component hesperidin as observation index. RESULTS： The optimal extracting technology for hesperidin were as follows： 95% methanol （50 ml） were added for refluxing of 1 hour. CONCLUSION： The optimized extraction technology serves as a reliable scheme for determination of the content of hesperidin in Jianpi granules and thus ensuring the quality of Jianpi granules.
出处
《中国医院用药评价与分析》
2013年第5期446-448,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
正交设计
橙皮苷
提取工艺
Orthogonal design
Hesperidin
Extraction technology
