摘要
阻塞性睡眠呼吸暂停低通气综合征(OSAHS)可诱发舒张性心力衰竭,引起多种临床症状,对患者预后及生活质量产生更多不良影响。其主要病理生理学变化为慢性间歇性或持续性乏氧和高碳酸血症。舒张性心力衰竭发生机制复杂,OSAHS可通过乏氧、神经系统功能改变、炎症反应及水钠潴留而诱发或加重舒张性心力衰竭。OSAHS与舒张性心力衰竭有密切关系,OSAHS可引起并加重心衰,而心衰患者可能会伴发OSAHS,其互为因果,互相促进。在临床治疗方面,我们应充分重视两者相关性及其危害性,制定合理治疗方案。
Obstructive sleep apnea hypopnea syndrome （OSAHS） can induce diastolic heart failure, causes a variety of clinical symptoms, leads to many adverse impacts on the prognosis and quality of life. The main pathophysiology of OSAHS is chronic in- termittent or persistent hypoxia and hypercapnia. The mechanisms of diastolic heart failure is complicated. The OSAHS by lack of oxygen, nervous system function change, inflammatory response and overloaded fluidmay induce or aggravate diastolic heart fail- ure. There is very close relationship between OSAHS and diastolic heart failure. The OSAHS can cause and worsen heart failure, patients with heart failure may be associated with OSAHS, reinforce each other. In clinical treatment, we should pay full attention to the correlation between the two and its harmfulness to develop a reasonable treatment options
出处
《医学与哲学（B）》
2013年第5期12-13,共2页
Medicine & Philosophy(B)
