摘要
目的:观察中西医结合治疗幽门螺杆菌(HP)阳性慢性胃炎的临床疗效。方法:90例患者随机分为观察组和对照组各45例。对照组采用奥美拉唑胶囊20 mg+克拉霉素500 mg+阿莫西林1 000 mg,2次/d,疗程10 d。观察组加服用消幽护胃方,1剂/d,疗程4周。观察HP根除率,记录脾胃湿热证积分及不良反应。结果:观察组治疗后HP阴转35例(77.78%)优于对照组的26例(57.78%)(P<0.05);观察组综合疗效明显优于对照组(P<0.01);观察组中医证候疗效明显优于对照组(P<0.01);观察组上腹胀、上痛腹、胃脘灼热、口苦口臭、恶心呕吐等症状及脾胃湿热证积分均明显低于对照组(P<0.01);治疗过程中观察组未出现明显不良反应。结论:中西结合疗法有助于根除HP,提高临床疗效,并能明显改善临床症状,不良反应少,是临床值得使用的方案。
Objective： To observe the clinical efficacy on the treatment of chronic gastritis with masculine Helicobacter pylori（HP） by combination of traditional Chinese medicine（TCM） and western medicine.Method： Ninety patients were randomly divided into observation group and control group（n = 45 each）.Patients in two groups were treated with omeprazole capsules 20 mg,clarithromycin 500 mg and amoxicillin 1 000 mg（twice daily and ten days as one course） and Xiaoyou Huwei prescription（once a day,four weeks as one course） was applied in the observation group.Eradication rate of HP,spleen-stomach damp-heat syndrome and adverse reactions were recorded.Result： The negative conversion cases of HP in the observation group（35 cases,77.78%） were better than that of the control group（26 cases,57.78%）（P ＆lt; 0.05）.The therapeutic efficacy of the observation group was significantly better than the control group（P ＆lt; 0.01）.The effective rate of Chinese medicine syndrome in the observation group was better than the control group（P ＆lt; 0.01）.Accumulating points of big belly,abdominal pain,epigastric burning,ozostomia,nausea and vomitting,spleen-stomach damp-heat syndrome in the observation group were better than those in the control group（P ＆lt; 0.01）.No significant adverse reactions observed in the course of treatment.Conclusion： Combination of TCM and western medicine has better therapeutic efficacy,marked improvement in clinical symptoms and less adverse reactions,it could be chosen as the preferred alternative.
出处
《中国实验方剂学杂志》
CAS
北大核心
2013年第12期285-287,共3页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
慢性胃炎
幽门螺杆菌
中西医结合疗法
chronic gastritis
HP
combination of traditional Chinese medicine and western medicine
