期刊文献+

丙型肝炎失代偿期肝硬化的抗病毒治疗 被引量:4

Current perspectives on antiviral therapy in hepatitis C-infected patients with decompensated cirrhosis
原文传递
导出
摘要 丙型肝炎肝硬化代偿期患者每年发展为失代偿期的比例为3.6%~6.0%,目前惟一有效的治疗方法是肝移植。由于肝移植费用高、供肝短缺以及肝移植后复发率高,因此,国内外研究者对失代偿期肝硬化患者尝试着进行抗病毒治疗。通过清除HCV可改善患者的肝功能,延缓疾病进展,减少肝脏失代偿,部分患者甚至免于肝移植,延长患者的生存期。但是抗病毒治疗的时机、剂量和疗程、疗效尚不是很明确。
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2013年第6期413-414,共2页 Chinese Journal of Hepatology
关键词 肝炎病毒 丙型 肝硬化 治疗 Hepatitis C virus Liver cirrhosis Therapy
  • 相关文献

参考文献13

  • 1Asian Pacific Association for the Study of the Liver (APASL) Hepatitis C Working Party, McCaughan GW, Omata M, et al. Asian Pacific Association for the Study of the Liver consensus statements on the diagnosis, management and treatment of hepatitis C virus infection. J Gastroenterol Hepatol, 2007, 22:615-633. 被引量:1
  • 2陈文,王鲁文,袁念芳,龚作炯.小剂量α-干扰素治疗失代偿期丙型肝炎肝硬化的疗效观察[J].实用肝脏病杂志,2008,11(3):174-175. 被引量:10
  • 3纪泛扑,李政霄,蔡芝芳,田长印,薛红安,潘国英,邓红.普通干扰素逐渐加量治疗失代偿期丙型肝炎肝硬化的短期疗效及安全性[J].中华肝脏病杂志,2010,18(12):946-948. 被引量:6
  • 4杨松,成军.2011年EASL《丙型肝炎病毒感染管理指南》要点解读[J].中国肝脏病杂志(电子版),2011,3(2):46-50. 被引量:3
  • 5Crippin JS, McCashland T, Terrault N, et al. A pilot study of the tolerability and efficacy of antiviral therapy in hepatitis C virus- infected patients awaiting liver transplantation. Liver Transpl, 2002, 8: 350-355. 被引量:1
  • 6Thomas RM, Brems JJ, Guzman-Hartman G, et al. Infection with chronic hepatitis C virus and liver transplantation: a role for interferon therapy before transplantation. Liver Transpl, 2003, 9: 905 -915. 被引量:1
  • 7Forns X, Garcia-Retortillo M, Serrano T, et al. Antiviral therapy of patients with decompensated cirrhosis to prevent recurrence of hepatitis C after liver transplantation. J Hepatol, 2003, 39: 389-396. 被引量:1
  • 8Everson GT, Trotter J, Forman L, et al. Treatment of advanced hepatitis C with a low accelerating dosage regimen of antiviral therapy. Hepatology, 2005, 42: 255-262. 被引量:1
  • 9Iacobellis A, Siciliano M, Perri F, et al. Peginterferon alfa-2b and ribavirin in patients with hepatitis C virus and decompensated cirrhosis: a controlled study. J Hepatol, 2007, 46: 206-212. 被引量:1
  • 10Carri6n JA, Martinez-Bauer E, Crespo G, et al. Antiviral therapy increases the risk of bacterial infections in HCV-infected cirrhotic patients awaiting liver transplantation: a retrospective study. J Hepatol, 2009, 50: 719-728. 被引量:1

二级参考文献21

  • 1丙型肝炎防治指南[J].临床肝胆病杂志,2004,20(4):197-203. 被引量:735
  • 2Iacobellis A,Siciliano M,Perri F,et al.Peginterferon alfa-2b and ribavirin in patients with hepatitis C virus and decompensated cirrhosis:a controlled study.J Hepatol,2007,46:206-212. 被引量:1
  • 3Carrión JA,Martínez-Bauer E,Crespo G,et al.Antiviral therapy increases the risk of bacterial infections in HCV-infected cirrhotic patients awaiting liver transplantation:A retrospective study.J Hepatol,2009,50:719-728. 被引量:1
  • 4Everson GT,Trotter J,Forman L,et al.Treatment of advanced hepatitis C with a low accelerating dosage regimen of antiviral therapy.Hepatology,2005,42:255-262. 被引量:1
  • 5Forns X,García-Retortillo M,Serrano T,et al.Antiviral therapy of patients with decompensated cirrhosis to prevent recurrence of hepatitis C after liver transplantation.J Hepatol,2003,39:389-396. 被引量:1
  • 6Ghany MG,Strader DB,Thomas DL,et al.Diagnosis,management,and treatment of hepatitis C:an update.Hepatology,2009,49:1335-1374. 被引量:1
  • 7Yu ML,Chuang WL.Treatment of chronic hepatitis C in Asia:when East meets West.J Gastroenterol Hepatol,2009,24:336-345. 被引量:1
  • 8Ge D,Fellay J,Thompson A J,et al.Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance.Nature,2009,461:399-401. 被引量:1
  • 9TASSOPOULOS NC. Patterns of progression:unpredictability and risk of decompensated cirrhosis [J]. Dig Dis Sci, 1996,41:41S-48S. 被引量:1
  • 10FATTOVICH G,GIUSTINA G,DEGOS F,et al. Morbidity and mortality in compensated cirrhosis type C:a retrospective follow-up study of 384 patients [J]. Gastroenterology, 1997, 112: 463-472. 被引量:1

共引文献25

同被引文献22

引证文献4

二级引证文献30

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部