摘要
目的:观察地黄饮子对冠心病心功能不全患者(阳气虚衰型)的临床疗效。方法:选取符合纳入标准的60例基础疾病为冠心病且NYHA心功能分级为Ⅱ级和Ⅲ级、中医辨证属阳气虚衰型患者为研究对象,随机分为对照组和治疗组,各30例,对照组给予基础治疗,治疗组在基础治疗的基础上联合地黄饮子治疗,疗程为4周。结果:治疗组左室射血分数(LVEF)及6分钟步行距离(6MWT)较治疗前增加(P<0.05),心率变异性分析中24小时内全部正常心动周期的标准差(SDNN)较治疗前改善(P<0.05);治疗后两组比较,治疗组较对照组的LVEF及6WMT增加、SDNN改善更明显(P<0.05)。结论:地黄饮子能够增加冠心病心功能不全患者的左室射血分数及6分钟步行距离,改善心率变异性。
Objective：To observe the clinical curative effect of radix rehmanniae YinZi on coronary heart disease patients with cardiac insufficiency （ Yang Deficiency）. Methods ： Select 60 cases of patients with coronary heart disease and heart function NYHA classification for the level and stage TCM syndrome differentiation of Yang Deficiency type as the research objects, and then divide the groups into control group and treatment group, 30 cases in each group and the control group received the foundation treatment, while the treatment group received basic treatment on the basis of Radix rehmannia YinZi, the course was for four weeks. Results ： Left ventricular ejection fraction （LVEF） and six minute walking distance （6 MWT）increased in the treatment group after treatment（P 〈0.05 ）, and heart rate variability during 24 hours all normal cardiac cycle of standard deviation （SDNN）was improved after treatment（P 〈0.05 ）. LVEF and 6WMT were increased and SDNN was improved obviously in the treatment group compared with the control group （ P 〈 0.05 ）. Conclusion ： Radix rehmanniae Yinzi can increase the score of LVEF and six -minute walking distance and improve heart rate variability among coronary heart disease patients with cardiac insufficiency.
出处
《中医药信息》
2013年第3期90-91,共2页
Information on Traditional Chinese Medicine
关键词
地黄饮子
心功能不全
左室射血分数
心率变异性分析
6分钟步行距离
Radix rehmanniae YinZi
Cardiac insufficiency
Left ventricular ejection fraction
Heart rate vari- ability analysis
Six- minute walking distance
