摘要
目的观察中西医结合治疗儿童咳嗽变异性哮喘（CVA）的疗效。方法将2010年1月至2011年12月我院儿科门诊就诊CVA患儿85例,病例随机分为两组,对照组采用丙酸氟替卡松气雾剂（ICS）吸入,;治疗组在对照组用药的基础上,根据中医辨证分型,分别加服本院自制中药麻杏清肺口服液、芪风健中口服液、芪芍健脾口服液。治疗共8周。研究期间共有6次访视,评估治疗组、对照组经治疗后CVA患儿症状评分、最大呼气峰流（PEF）值变化和1年内复发率。结果对照组患儿症状评分（治疗前4.0~治疗7周0.84）,治疗组患儿症状评分（治疗前4.3~治疗7周0.34）两组均有明显下降（P均〈0.01）;对照组PEF值（治疗前65.06%~治疗7周89.54%）,治疗组PEF值（治疗前65.68%~治疗7周96.74%）两组均有明显升高（P均〈0.001）;两组比较以治疗组为更优（P〈0.05）。对照组1年内复发率28.57%,治疗组1年内复发率6..98%,两组比较有显著意义（P〈0.05）。结论 ICS吸入联合中药治疗,能更好地改善CVA患儿的症状评分、提高PEF值、减少复发率,值得临床推广和应用。
Objective Observed integrative efficacy of the treatment of children with cough variant asthma （CVA）. Method 85 cases who were diagnosed as CVA in Pediatrics of our hospital during 2010.01 to 2011.12 were randomly divided into two groups. Control group cases were treated by fluticasone propionate aerosol （ICS）, treatment group cases raked hospital homemade Chinese medicine respectively （Maxing Qingfei oral Liquid, Qifeng Jianzhong Oral Liquid, Qi Shao Jian Pi oral solution）, which were based on typing differentiation to traditional Chinese medicine. Course of treatment was 8 weeks. Symptom scores, peak expiratory flow （PEF） values change and 1-year recurrence rate were assessed in two groups during 6 follow-up. Result Score on symptoms were significantly reduced in both groups （P〈0.01）.Peak expiratory flow （PEF） were significantly increased in both groups, 1-year recurrence rate of control group was 28.57%, and was 6..98% in treatment group. The Difference was significantly between control group and treatment group（P〈0.05）. Conclusion The treatment combined ICS inhalation and Chinese medicine can improve the Symptom scores, increase .Peak expiratory flow and reduce 1-year recurrence rate, so this therapy worthy of clinical application.
出处
《中国医药指南》
2013年第10期18-20,共3页
Guide of China Medicine
