摘要
目的:观察碱性成纤维细胞生长因子(bFGF)治疗复发性口腔溃疡的临床效果。方法:83例复发性口腔溃疡患者随机分为观察组43例和对照组40例。观察组给予bFGF直接喷涂于溃疡面,4次/d;对照组予0.9%的生理盐水液漱口,4次/d。就诊后开始治疗,治疗1周后作评价。结果:观察组的有效率达90.7%,显著高于对照组的57.5%(P<0.01);观察组的溃疡平均愈合时间比对照组缩短(P<0.01)。结论:bFGF对复发性口腔溃疡有显著的临床治疗效果。
Objective： To observe the clinical effect of bFGF for the treatment of recurrent aphthous ulcer（RAU）. Methods： 83 patients with RAU were randomly divided into the observation group with 43 cases and control group with 40 cases. The observation group was given bFGF to spray directly on the ulcer surIace, 4/d; the control group were given 0.9 % physiological saline to gargle, 4/d. After the start of treatment, done evaluation was 1 week after treatment. Results： In observation group, the effective rate was up to 90.7%, significantly higher than that of con trol group 57.5 % （P〈0.01） ; meanwhile, in the observation group, the average healed time of ulcer was shortened group （P%0.01）. Conclusion： bFGF has significant effect on the treatment of RAU.
出处
《口腔医学研究》
CAS
CSCD
2013年第5期476-477,共2页
Journal of Oral Science Research
关键词
碱性成纤维细胞生长因子
复发性口腔溃疡
临床疗效
Basic fibroblast growth factor（bFGF） Recurrent aphthous ulcer（RAU） Clinical effectiveness
