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大蒜素联合维生素对复发性口腔溃疡患者的临床研究 被引量:5

Clinical efficacy of allicin combined with vitamin in patients with recurrent oral ulcer
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摘要 目的 探讨大蒜素联合维生素治疗复发性口腔溃疡的临床效果.方法 回顾性分析我院于2013年1月至2014年5月收治的108例(ROU)患者的临床资料,对照患者采用康复新液治疗,而观察组患者使用大蒜素联合维生素B2治疗,对比两组患者的临床疗效及疼痛指标情况以及T淋巴细胞亚群(CD3、CD4、CD8).结果 治疗后,观察组患者的总有效率为98.15%,明显高于对照组患者,组间比较差异具有统计学意义(P<0.05),同时,观察组患者的疼痛指标较对照组患者出现明显改善,且观察组患者的T淋巴细胞亚群检测结果较对照组患者出现明显改善,组间比较差异亦具有统计学意义(P<0.05).结论 大蒜素联合维生素B2治疗ROU具有协同效果,不但可以有效缓解患者的疼痛症状,而且还可以调节患者的机体免疫状态,促进局部受损黏膜的恢复,改善患者的病情,从而提高患者的生活质量,值得向临床推广和应用. Objective To investigate clinical efficacy of allicin combined with vitamin in the treatment of recurrent oral ulcer (ROU).Methods 108 patients with ROU in our hospital from January 2013 to May 2014 were selected and divided into two groups.Patients in control group were given Kangfuxin oral solution, while patients in observation group were given allicin combined with vitamin B2.Compared clinical efficacy of two groups.Results After treatment, the total effective rate of observation group was 98.15%, significantly higher than that of control group, with statistically significant difference (P〈0.05).Pain degree and T lymphocyte subsets test results of observation group significantly improved compared with control group, with statistically significant differences (P〈0.05).Conclusion Allicin combined with vitamin B2 in the treatment of ROU has a significant effect, which not only can effectively relieve pain symptoms, but also can regulate the immune status of patients, worthy of clinical promotion and application.
作者 孙晓辉
出处 《国际医药卫生导报》 2015年第20期3045-3048,共4页 International Medicine and Health Guidance News
关键词 大蒜素 维生素 复发性口腔溃疡 Allicin Vitamin Recurrent oral ulcer
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