摘要
目的观察体部伽玛刀序贯化疗治疗局部晚期非小细胞肺癌的近期疗效及不良反应。方法回顾性分析2007年12月—2009年1月我科收治的60例局部晚期非小细胞肺癌行体部伽玛刀序贯化疗治疗的临床资料。结果 60例患者全部完成了计划剂量治疗,治疗结束后3个月完全缓解(CR)者占28.3%,部分缓解(PR)者占60%,总有效者(CR+PR)占88.3%,1年生存率(OS)为56.7%。主要不良反应为骨髓抑制和消化道反应。结论体部伽玛刀序贯化疗治疗局部晚期非小细胞肺癌近期疗效高,毒副反应小。
Objective To observe the efficacy of body gamma knife sequential chemotherapy for locally advanced non-small cell lung cancer and its adverse reactions. Methods A retrospective analysis was done through the clinical data of 60 patients with locally advanced non-small cell lung cancer who had undergone body gamma knife sequential chemotherapy our department from December 2007 to January 2009. Results All the 60 patients completed the planned dose therapy. Three months later after the end of treatment, complete remission （CR） was reached in 28.3% of the patients, and partial remission （PR） in 60%. The total effective （ CR ＋ PR） rate was 88.3% , and one-year survival （OS） was 56.7%. The main adverse reactions were myelosuppres- sion and gastrointestinal reaction. Conclusion Sequential chemotherapy with body gamma knife is of short-term efficacy on locally advanced non-small cell lung cancer, and has slightly toxic.
出处
《临床军医杂志》
CAS
2013年第5期497-499,共3页
Clinical Journal of Medical Officers
关键词
体部伽玛刀
化疗
肺肿瘤
非小细胞肺癌
body gamma knife
chemotherapy
lung tumor
non-small cell lung cancer
