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长春西汀治疗脑梗死伴脑微出血的临床研究

Effect of the Rho-kinase inhibitor in cerebral infarct with cerebral microbleeds
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摘要 目的探讨长春西汀治疗对脑梗死伴脑微出血(CMBs)影响。方法根据头颅GRE-MRI序列的结果,选取CMBs阳性脑梗死患者30例,随机分为观察组30例和对照组各30例,入组者进行脑梗死常规治疗,在此基础上治疗组给予法舒地尔治疗14d。根据治疗前后NIHSS评分的变化评定临床疗效。结果观察组临床疗效优于对照组,差异有统计学意义(P<0.05)。结论长春西汀可以改善脑梗死伴脑微出血患者临床症状。 Objective To observe the effect of vinpocetine in cerebral infarction patients with cerebral microbleeds (CMBs). Methods Sixty cases of cerebral infarction patients with CMBs were chosen and divided randomly into two groups. Thirty cases of patients in treatment group were given conventional treatments combined with vinpocetine, thirty cases in control group were given conventional treatments. All the patients were treated for two weeks. The both groups were evaluated by National Institutes of Health Stroke Scale (NIHSS) and the results were compared between the two groups. Results There was no significant difference in NIHSS score between the two groups before treatment. After the two weeks of admission, the results of NIHSS of the two groups both decreased (P 〈 0.05), but vinpocetine group decreased more than control group (P〈0.05). And the therapeutic efficacy between the two groups had statistical difference (P〈0.05). Conclusion Vinpocetine is saf, and has great effeet on cerebral infarction with CMBs.
出处 《中国卫生产业》 2013年第12期9-10,13,共3页 China Health Industry
基金 黑龙江省卫生厅基金项目2012-402
关键词 脑梗死 脑微出血 长春西汀 Cerebral infarction Cerebral microbleeds Vinpocetine
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