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有上消化道症状患儿幽门螺杆菌感染的研究 被引量:6

Study of Helicobacter Pylori Infection for Children with Upper Gastrointestinal Symptoms
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摘要 目的对有上消化道症状的患儿进行幽门螺杆菌感染相关研究。方法 2007年6月-2011年12月因上消化道症状来院治疗的患儿共348例分为:A组(<6岁)41例,B组(6~9岁)101例,C组(9~12岁)115例,D组(>12岁)91例。所有患者均行电子胃镜检查,并取活检行细菌培养及病理切片。结果 H.pylori阳性率为52.6%。H.pylori阳性组炎性活动性发生率高于H.pylori阴性组,差异有统计学意义(χ2=103.013,P=0.000)。H.pylori阳性组炎症活动程度集中在轻、中度,而H.pylori阴性组则主要集中在轻度。H.pylori阳性组胃黏膜炎症以中度为主,H.pylori阴性组胃黏膜炎症以轻、中度为主。结论儿童时期是H.pylori的易感期,应尽早诊断和治疗儿童H.pylori感染。 Objective To study the infection of helicobacter pylori for children with upper gastrointestinal symptoms. Methotis A total of 348 children with upper gastrointestinal symptoms from June 2007 to December 2011 in our hospital were divided into 4 groups:41 cases in A group( 〈6 years) ,101 cases in B group(6 -9 years) ,115 cases in C group(9 -12 years old) ,and 91 cases in D group( 〉 12 years). All patients underwent bacterial culture and biopsy. Results H. pylori-positive rate was 52. 6%. The incidence of inflammatory activity in the H. pylori-positive group was higher than in the H. pylori negative group, there was statistically significant( X2 = I03. 013 ,P = 0.000 ). In the H. pylori-positive group, the degree of" inflammatory activity concen- trated in the mild and moderate degree, while concentrated in mild degree in the H. pylori negative group. Gastric mucosal inflam- mation in the H. pylori-positive group mainly concentrated in the moderate degree, and concentrated in the mild and moderate de- gree in the H. pylori-negative group. Conclusion Childhood was the susceptible period to H. pylori, and it needed early diagnosis and treatment for children with H. pylori infection.
出处 《中华全科医学》 2013年第7期1055-1056,共2页 Chinese Journal of General Practice
关键词 幽门螺杆菌 感染 儿童 黏膜 病理 Helicobaeter pylori Infection Children Mucosa Pathology
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