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2型糖尿病患者颈动脉内中膜厚度与尿蛋白排泄率的相关性

Association of carotid artery intima-media thickness and 24-hour total urine protein in type 2 diabetic patients
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摘要 目的探讨2型糖尿病(T2DM)患者颈动脉内中膜厚度(CIMT)与尿蛋白排泄率的关系。方法 167例T2DM患者根据CIMT水平分为两组:A组116例(CIMT>0.9mm);B组51例(CIMT≤0.9mm)。检测两组CIMT和24-h尿蛋白定量。结果 A组年龄、全血白细胞、血浆纤维蛋白原和24-h尿蛋白定量高于B组(P<0.05)。年龄、糖尿病程、血浆纤维蛋白原和24-h尿蛋白定量与CIMT呈正相关(P<0.05)。24-h尿蛋白定量、年龄是CIMT的独立相关因素(P<0.05)。结论年龄联合24-h尿蛋白定量可能是T2DM患者CIMT的独立预测因素。 Objective To explore the relationship between carotid artery intima- media thickness(CIMT) and 24-hour total urine protein in the patients with type2 diabetes mellitus (T2DM). Methods CIMT and 24-hour total urine protein were examined in 167 T2DM cases, who were assigned into 2 groups of A (116 cases with CIMT〉0. 9 mm),B (51 cases with CIMT≤0. 9 mm). Results Age,white blood cell, fibrinogen(Fib), 24-hour total urine protein were higher in group A than those in group B(P〈0. 05). CIMT was positively correlated with the age, duration of DM, Fib and 24-hour total urine protein(P〈0. 05). Age and 24-hour total urine protein were independent factors for CIMT(P〈0. 05). Conclusion The age and 24-hour total urine protein are the independent risk factors for CIMT in T2DM patients.
出处 《江苏医药》 CAS 北大核心 2013年第9期1045-1047,共3页 Jiangsu Medical Journal
关键词 2型糖尿病 颈动脉内中膜厚度 尿蛋白 Type 2 diabetes mellitus Carotid arteries intima-media thickness Urine protein
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