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化痰祛瘀通络方联合西药治疗风痰入络型急性脑梗塞随机平行对照研究 被引量:3

Huatanquyu Tongluo Decoction combined with Western Medicine Treatment of Fengtan Ruluo Type Acute Cerebral Infarction Randomized and Controlled Study
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摘要 [目的]观察化痰祛瘀通络方联合西药治疗风痰入络型急性脑梗塞疗效。[方法]使用随机平行对照方法,将103例住院及门诊患者按就诊顺序随机分为两组,对照组51例西医常规治疗,治疗组52例化痰祛瘀通络方(生黄芪30g,半夏20g,丹参、当归各15g,生地黄20g,川芎、赤芍、三七各15g,水蛭、石菖蒲、葛根、川牛膝、酒大黄各10g)1剂/d,水煎2次,取混合液汁400mL分早晚口服,口服困难者予鼻饲给药。言语不清加远志10g以祛痰宣窍,痰瘀交阻加桃仁10g以活血化瘀;风阳上扰加天麻10g以平肝潜阳。西药治疗同对照组。连续治疗15d为1疗程。观测临床症状、血液流变学指标。连续治疗3疗程,判定疗效。[结果]治疗组痊愈11例,显效15例,有效20例,无效6例,总有效率88.46%;对照组痊愈8例,显效13例,有效15例,无效16例,总有效率70.59%,治疗组疗效优于对照组(P<0.05);血液流变学指标均有改善(P<0.05,P<0.01),治疗组改善优于对照组(P<0.01)。[结论]化痰祛瘀通络方联合西药治疗风痰入络型急性脑梗塞疗效确切,改善血液流变学指标,缓解脑细胞缺氧、缺血和脑循环障碍。 [ Objective ] The observation Huatanquyu Tongluo decoction combined with Western medicine treatment of Fengtan Ruluo acute cerebral infarction. [ Method] Randomized controlled method, 103 eases of hospitalized patients were randomly divided into two groups by random number table method, the control group of 51 patients with conventional Western treatment Tongluo Fang Huatanquyu treatment group, 52 patients ( Health Astragalus 30g, Pinellia 20g, Salvia 15g, angelica 15g, rehmannia 20g, Chuanxiong 15g, red peony, Panax each 15g, leeches 10g, Shiehangpu 10g, arrowroot10g, Cyathula rhubarb wine 10g) 1 times/day, decoction, take mixedjuice 40Oral sooner or later, such as clothing, oral difficult to nasal administration. Slurred speech plus Polygala 10g expectorant Orifices, plus peach kernel lOg phlegm resistance to blood circu- lation; the disturbance plus wind -yang the Gastrodia FOg to Pinggan were qianyang. Western medicine with the control group. Continuous treatment 15d for a course of treatment. Observation of clinical symptoms, he- morheology. Continuous treatment for 3 cycles to determine efficacy. [ Results ] Treatment group, 11 cases were cured, 15 eases markedly effective in 20 eases, 6 eases, total effective rate of 88.46% ; control group, 8 eases were cured, 13 eases markedly effective in 15 cases, ineffective in 16 cases, the total effective rate was 70.59% in the treatment groupmore effective than the control group (P 〈 0. 05) ; Hemorheologieal indexes were improved (P 〈0. 05, P 〈0. 01 ) , improvement in the treatment group than the control group (P 〈0. 01 ). [ Conclusion]Tongluo Huatanquyu combined western medicine wind phlegm into the network acute cerebral infarction exact, improve hemorheology relieve brain hypoxia, ischemia, and brain circulation disorders.
作者 甘俊鹤
出处 《实用中医内科杂志》 2013年第2期109-111,共3页 Journal of Practical Traditional Chinese Internal Medicine
关键词 急性脑梗塞 风痰入络 中风 化痰祛瘀通络方 血液流变学指标 中西医结合治疗 随机平行对照研究 Acute cerebral infarction Fengtan Ruluo Stroke the Huatanquyu Tongluo decoction Hemorheology Integrative Medicine Randomized and controlled study
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