摘要
目的:观察注射用鼠神经生长因子对视神经挫伤的临床疗效。方法:选择的46例(46眼)视神经挫伤患者,并将其随机分成治疗组23例(23眼),对照组23例(23眼)。治疗组在对照组的基础上给予注射用鼠神经生长因子30μg肌肉注射,1次/d,疗程4周,部分病例6周。对照组给予大剂量激素冲击治疗及综合治疗。随访6个月~1年观察注射用鼠神经生长因子的疗效。结果:治疗组的有效率为78.26%.对照组的有效率为52.17%,两组比较差异有显著性(x^2=6.757,P=0.034)。结论:注射用鼠神经生长因子治疗视神经挫伤有显著疗效,可促进视功能的恢复,提高视力。
Objective：To assess the effects of mice nerve growth factor （NGF） on optic nerve contusion. Methods： Forty-six patients with unilateral optic nerve contusion were randomly assigned to receive high-dose corticosteroid plus integrated treatment （ treatment group, n = 23 ） or in combination with mice nerve growth factor intramuscular injection （30μg once daily for four weeks and in some cases 6 weeks） （control group, n = 23）. A follow-up period of between 6 months and a year was scheduled. Results： The effectiveness rate was considerably higher in treatment group than in control group （78.26% vs. 52.17% , X2 =6. 757, P =0. 034）. Conclusion： Mice nerve growth factor is effective for the treatmem of optic nerve contusion owing to its capacity of promoting functional recovery leading to increased visual accuracy.
出处
《广州医学院学报》
2013年第1期29-30,共2页
Academic Journal of Guangzhou Medical College
关键词
注射用鼠神经生长因子
视神经挫伤
疗效观察
mice nerve growth factor for injection
optic nerve contusion
efficacy assessment
