摘要
目的探讨超声引导经皮微波消融结合门静脉灌注化疗对肝癌门静脉癌栓的预防作用。方法 78例未形成门静脉癌栓的原发性肝癌患者,采用微波消融结合门静脉灌注化疗治疗;治疗后定期对所有患者进行肝癌血清学指标癌胚抗原(AFP)检测,超声或CT检查肿瘤新生结节及门静脉癌栓形成情况,并随访患者复发率及生存率。结果 78例患者0.5a,1 a,2 a,3 a复发率分别为5%,12%,21%,36%,生存率分别为97%,95%,76%,40%。3 a间患者均无一例门静脉癌栓发生。结论超声引导经皮微波消融联合门静脉灌注化疗治疗肝癌疗效明显并可延长患者生存期,对门静脉癌栓的形成有明显的预防作用。
Objective It is to investigate the preventive value of percutaneous microwave ablation and portal vein perfusion chemotherapy on hepatoeellular carcinoma （HCC） with portal vein tumor thrombus （PVTT） under ultrasound guidance. Methods 78 cases of hepatocellular carcinoma without PVTT in the portal vein were treated with microwave ablation and portal vein perfusion chemotherapy. At regular intervals, the fetoprotein （AFP） were detected, and the new tumor nodules and por- tal vein tumor thrombus were examined by ultrasound or CT. The recurrence rate and survival rate of all the cases were fol- lowed up. Results The recurrence rate of 0.5 - , 1 - , 2 - , 3 - year was 5% , 12% , 21% , 40% , and the survival rate was 97% , 95% , 76% , 40% respectively. There was no PVTT in the moment of three years. Conclusion Percutaneous micro- wave ablation and portal vein perfusion chemotherapy under ultrasound guidance can improve the curative effect and increase survival rate, so it can prevent portal vein tumor thrombus significantly.
出处
《现代中西医结合杂志》
CAS
2013年第15期1609-1611,共3页
Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词
超声介入
微波消融
肝癌
门静脉癌栓
局部灌注
ultrasound intervention
microwave ablation
hepatic cancer
portal vein tumor thrombus
regional perfusion
