摘要
目的:观察自拟中药方联合阿奇霉素治疗小儿支原体肺炎的临床疗效。方法:将我院65例支原体肺炎患儿随机分为两组。对照组32例,先静脉滴注阿奇霉素10mg/kg,qd,连用5d,停用3d后改用口服阿奇霉素分散片,10mg/kg,连用3d,11d为一个疗程;治疗组33例在对照组的基础上加用我院自拟中药方治疗,每日1剂,水煎2次,兑匀,分2次温开水服用,连服11d为一个疗程。观察两组患儿的症状、体征、X线胸片等改善情况和不良反应发生情况。结果:治疗组患儿的总有效率为96.97%,显著高于对照组患儿(71.88%),两组比较差异有统计学意义(P<0.05)。两组患儿不良反应发生率比较,差异无统计学意义(P>0.05)。结论:我院自拟中药方联合阿奇霉素治疗小儿支原体肺炎疗效显著,安全性较好。
OBJECTIVE：To observe the clinical efficacy of TCM prescription and azithromycin for pediatric mycoplasma pneumonia.METHODS：65 cases of pediatric mycoplasma pneumonia in our hospital were randomized into 2 groups.32 cases in control group received intravenous dripping of azithromycin 10 mg/kg,qd,for consecutive 5 days;after stop taking medicine for 3 days,control group was given azithromycin 10 mg/kg orally for consecutive 3 days.A treatment course lasted for 11 days.33 cases in treatment group additionally received self-made TCM prescription on the basis of control group,one medicament each day,decocting for 2 times,twice a day,11 days as a period of treatment.The symptom,signs and chest X-ray as well as ADR were observed in 2 groups.RESULTS：The total effective rate of treatment group was 96.97%,which was higher than 71.88% in control group;there was significant difference between 2 groups（P0.05）.There was no statistical significance in the incidences of ADR between 2 groups（P0.05）.CONCLUSIONS：The self-made TCM prescription of our hospital combined with azithromycin is effective and safe for pediatric mycoplasma pneumonia.
出处
《中国药房》
CAS
CSCD
2013年第20期1875-1876,共2页
China Pharmacy
关键词
自拟中药方
阿奇霉素
小儿支原体肺炎
Self-made TCM prescription
Azithromycin
Pediatric mycoplasma pneumonia
