摘要
目的:探讨纤维蛋白原(Fibrinogen,FIB)含量与冠状动脉病变的相关性以及与其他危险因素的关系。方法:选取我院收治确诊冠心病患者178例,依据其冠脉病变程度分为三组,检测肝肾功能、血脂、血糖、血常规、FBI,并设置冠脉造影结果正常或是主要冠脉狭窄程度<50%的患者148例为对照组,进行对比分析。结果:冠脉病变血管支数越多FIB水平愈高,血浆FIB水平和冠脉病变血管支数呈明显相关性(P<0.01);冠心病组和对照组FBI、TG、LDL-C、TC、HDL-C、ApoAI、ApoB差异显著(P<0.05)。结论:血浆FBI水平与冠脉病变相关;且年龄、吸烟史、糖尿病史与冠心病明显相关,FBI可作为冠脉病变程度的预测指标之一。
Objective：To discuss the association of fibrinogen （FIB） content with coronary artery lesions and other risks factors. Methods： A total of 178 patients with confirmed coronary heart disease （CHD） admitted to our hospital were enrolled and divided into three groups according to the degree of coronary artery lesion. Renal function, blood lipid, blood sugar, blood routine examination and FIB were measured. Meanwhile, 148 patients with normal coronary angiogram results or degree of coronary main artery stenosis ;50; were chosen as control group for comparison. Results： The more the number of stenosis vessels was, the higher FIB level was. FIB was correlated with the number of stenosis vessels （P〈0.01）. There were significant differences between CHD group and control group in FBI, TG, LDL-C, TC, HDL-C, ApoAI and ApoB （P〈0.05）. Conclusions： Serum FIB level is related with coronary artery lesion which is associated with age, smoking history, diabetes history and CHD. FIB could be regarded as one of predictive index for the degree of coronary artery lesion.
出处
《海南医学院学报》
CAS
2013年第5期614-616,共3页
Journal of Hainan Medical University
基金
中国高校医学期刊临床专项资金项目(112210628)~~
关键词
纤维蛋白原
含量
血脂
冠脉病变
Fibrinogen
Content
Blood lipid
Coronary artery lesions
