摘要
目的观察急性心肌梗死患者血浆纤维蛋白原(FIB)及C反应蛋白(CRP)水平,探讨两者间的关系以及对急性心肌梗死治疗的临床意义。方法测定经冠状动脉造影确诊为急性心肌梗死85例的血浆纤维蛋白原及C反应蛋白水平,分析FIB与CRP的相关性。结果偏相关分析显示,急性心肌梗死患者FIB与CRP明显相关,相关系数r=0.592,P<0.01。结论FIB不仅在凝血途径中起决定性作用,而且参与体内炎症反应,加剧冠脉病变进展,为一项简便易测的重要临床监测指标。
Objective To investigate the relationship between the levels of plasma fibrinogen and C reactive protein, in patients with acute myocardial infarction. Methods The levels of plasma fibrinogen and C reactive protein were measured in 85 cases of acute myocardial infarction,using coronary angiography. The relationship between plasma fibrinogen and C reactive protein was analyzed. Result Partial correlation analysis showed that plasma fibrinogen was positively correlated with C reactive protein. (r =0.592, P<0.01). Conclusion Plasma fibrinogen participated in inflammatory reaction, aggravated evolution of diseased coronary artery as well as possessed decisive role in mechanism of blood coagulation.
出处
《世界临床药物》
CAS
2007年第5期266-268,273,共4页
World Clinical Drug
关键词
急性心肌梗死
纤维蛋白原
C反应蛋白
acute myocardial infarction
fibrinogen
C reactive protein
