摘要
目的:探讨经带宁胶囊配合中药外用法对子宫内膜异位症腹腔镜术后患者进行巩固治疗的临床疗效。方法:将50例子宫内膜异位症腹腔镜术后患者随机分为2组,治疗组25例术后进行中药综合疗法(口服经带宁胶囊、中药灌肠及中药外敷),连续治疗3个月,对照组25例术后应用长效GnRHa治疗。3个月后对2组患者治疗前后痛经程度缓解,CA125、EMAb的变化,伴随症状(肛门坠痛、性交痛、经期延长、经量过多等)等情况进行比较。结果:治疗后2组患者痛经症状及伴随症状较治疗前明显改善,血清CA125水平及EMAb阳性率均显著下降(均P<0.05);2组间比较差异无统计学意义(P>0.05)。结论:经带宁配合中药外用与GnRHa皮下注射均可改善子宫内膜异位症症状及病理基础,但中药多途径联合疗法较GnRHa皮下注射费用低,且治疗期间没有任何不适感,如有生育要求的患者在完成治疗后即可备孕,免除患者由于等待产生的焦虑情绪。
Objective To explore the clinical efficacy of consolidation therapy after laparoscopic surgery with Jingdaining capsule combining with external use of Chinese herbnal drugs for patients with endometriosis. Methods 50 patients with uterine endometriosis after laparoscopic surgery were randomly divided hto two groups, 25 cases of treatment group of postoperative combined therapy of Traditional Chinese Medicine（oral the Jingdaining capsules, medicine enema, TCM herbs external use）, continuous treatment for 3 months. Another 25 patients of the control group were treated with long-acting GnRHa thrapy for 3 months. After treatment, dysmenorrhea severity score, the changes of the serum level of CA125 and EMAb, and the concomitant symptoms of patients were compared between two groups. Results The dysmenorrhea severity score and concomitant symptoms after treatment were improved significantly comparing with those of prior treatment（P〈0.05）. The serum level of CA125 and positive ratio of EMAb were decreased notably （P〈 0.05）, comparing with mose of pretherapy. There was no statistically significance between two gr0ups（P 0.05）. Conclusion The therapy of Jingdaining capsule combining with the external use of Chinese herbnal drugs and that of GnRHa subcutaneous injection may both improve the symptoms of endometriosis and pathological basis, but Chinese medicine combination therapy in many ways costs lower than GnRHa subcutaneous injection treatment, and there is no any discomfort during treatment. Patients with fertility requirements could prepare for pregnant after the completion of treatment, and exempt the anxiety generated due to waiting for pregnancy.
出处
《深圳中西医结合杂志》
2013年第2期94-97,共4页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
关键词
子宫内膜异位症
腹腔镜
经带宁
中药外用
Laparoscopy
Jingdaining capsule
Chinese herbal drugs
External use
