摘要
目的:探讨柴芩温胆乌贝汤治疗反流性食管炎的疗效及其机制。方法:将68例反流性食管炎病例随机分为中医治疗组和西药对照组各34例,治疗组给予柴芩温胆乌贝汤,对照组给予雷贝拉唑与莫沙必利治疗,8周后比较2组疗效及2组治疗前后血浆TNF-α、NO水平的变化情况。结果:2组疗效对比显示,治疗组较对照组有统计学意义,且2组均能降低RE患者血浆TNF-α、NO水平,治疗后治疗组较对照组有统计学意义。结论:柴芩温胆乌贝汤治疗反流性食管炎有较好疗效,其机制可能与其能影响TNF-α、NO水平有关。
Objective： To explore the clinical effect of Chaiqin Wendan Wubei Decoction on reflux esophagitis and to discuss the mecha- nism of it. Methods：Sixty-eight patients of reflux esophagitis were randomized to two groups, 34 patients in the Chinese medicine treat- ment group were treated by Chaiqin Wendan Wubei Decoction, and 34 patients in the Western medicine control group were treated by rabeprazole and mosapride. The plasma TNF- and NO level changes were compared before and after treatment after 8 weeks. Resuh： The effective rates were significantly different between the two groups. Both groups had reduced RE plasma TNF-ct and NO levels, and there were significant differences between the treatment group and the control group after treatment. Conclusion：Chaiqin Wendan Wubei Decoction is effective for treating reflux esophagitis and its mechanism seems to be related with the TNF-ct and NO levels.
出处
《世界中医药》
CAS
2013年第4期402-404,共3页
World Chinese Medicine
