摘要
报道了重水溶液中α 环糊精与对甲酚、间甲酚发生包结作用的1 HNMR研究结果 .实验发现 ,尽管未包结的α 环糊精和包结后的α 环糊精疏水腔中的同类质子有着不同的化学位移 ,但1 HNMR只检测到一个峰 ,且峰的位置随包结程度的变化而异 .由1 HNMR的数据计算得到了α 环糊精在不同包结程度下的平均几何结构和平衡常数 ,描述了客体在主体腔中进入深度动态变化的情形 ,并和 β 环糊精的结果进行了比较 .
The results of \{\}\+1H NMR investigation of α cyclodextrin inclusions with p and m cresol in heavy water are reported in this paper. It was found that though there is difference in chemical shift of some protons in α cyclodextrin cavity between after and before complexing with cresol, only singlet resonance peak had been detected by \{\}\+1H NMR, position of which was dependent upon the inclusive degree. The average geometrical structures of inclusion complexes and their equilibrium constants under different inclusive degrees had been calculated based on \{\}\+1H NMR data, and the situation of dynamic variation of entering depth of cresol into α cyclodextrin cavity had been described. Meanwhile, the comparison of the above results of α cyclodextrin with β cyclodextrin are made in this paper.
出处
《波谱学杂志》
CAS
CSCD
北大核心
2000年第1期63-67,共5页
Chinese Journal of Magnetic Resonance
基金
江苏石油化工学院科技基金资助项目
关键词
Α-环糊精
甲酚
NMR
包结物
异构体
动态结构
cyclodextrin, Cresol, \{\}\+1H NMR, Inclusion, Binding equilibrium, Dynamic structure
