摘要
目的为了观察气血双补胶囊治疗非小细胞肺癌化疗患者的疗效。方法将云南省红河州个旧市中医医院70例非小细胞肺癌患者随机分为治疗组和对照组,每组各35例。两组均采用吉西他滨联合顺铂化疗2个周期,即第1天使用吉西他滨每次1000 mg/m2联合顺铂75 mg/m2静脉滴注,每3周重复1次。3周为1个周期。治疗组于化疗前1周开始口服气血双补胶囊,每次3粒,每日3次,持续8周。结果治疗组Kamofsky评分增加优于对照组,差异有统计学意义(P<0.05)。治疗组和对照组有效率分别为42.9%和34.3%,差异无统计学意义(P>0.05)。治疗组血红蛋白减少发生率对照组明显减少,两组比较差异有统计学意义(P<0.05)。结论气血双补胶囊配合GP方案与单纯GP方案治疗肺癌的客观疗效相近,但前者生活质量,预防骨髓抑制,提高血红蛋白水平改善明显。
Objective To observe the effects of capsule for invigorating qi and blood in the treatment of non-small cell lung cancer patients undergoing chemotherapy. Methods Non-small cell lung cancer patients were randomly divided into treatment group and control group. Both groups were treated by two cycles of gemcitabine plus cisplatin chemotherapy, which is using gemcitabine 1000 mg/n~ plus cisplatin 75 mg/m2 by intravenous once for the first day, repeated once every three weeks. Three weeks was a cycle. In the week before chemotherapy, treatment group was us- ing capsule for invigorating qi and blood by oral, three capsules each time, three times a day, for eight weeks. Results Kamofsky score in treatment group increased more than control group, the difference between the two groups was significant （P 〈 0.05）. Effective rate in the treatment group and control group were 42.9% and 34.3% respectively, but there was no significant difference （P 〉 0.05）. Compared with control group, the incidence of hemoglobin reducing in treatment group was significantly decreased （P 〈 0.05）. Conclusion The efficacy of capsule for invigorating qi and blood with GP regimen was similar to simple GP regimen in treatment of lung cancer, but the former can significantly improve quality of life of the patients, prevent bone marrow suppression, and increase hemoglobin levels.
出处
《中国医药导报》
CAS
2013年第12期98-99,102,共3页
China Medical Herald
基金
上海市中医肿瘤优势专科建设项目(编号:2008YSZK008)
关键词
非小细胞肺癌
气血双补胶囊
化疗
吉西他滨
顺铂
Non-small cell lung cancer
Capsule for invigorating qi and blood
Chemotherapy
Gemcitabine
Cisplatin
