摘要
以柴胡、款冬花、远志等山西道地中药材为例,总结植物代谢组学技术在中药材质量评价中的应用。在中药材质量评价中,代谢组学侧重于对样本的客观分组聚类,同时可确定差异代谢物,与指纹图谱技术具有明显的互补性,可使中药质量标准更体现中药特色,提高其可控性。分析该技术的优势与应用前景,指出尚存在的问题和改进建议,为扩大其应用提供参考。
The application of plant metabolomic technology in the quality evaluation of traditional Chinese medicinal materials （TCMM） was reviewed, using BupIerui Radix, Farfarae Flos, Polygale Radix, and Astragali Radix as genuine medicinal materials. In quality evaluation of TCMM, not only the cluster, but also the differential metabolites between different groups could be revealed simultaneously by metabolomic technology. Thus, plant metabolomic technology is complimentary with fingerprint technology, the characteristics of TCMM could be reflected in quality standards, and the controllability could be also improved. The advantage as well as the prospect is discussed. In addition, the limitations of this technique are pointed and the improvement methods are also suggested.
出处
《中草药》
CAS
CSCD
北大核心
2013年第7期785-789,共5页
Chinese Traditional and Herbal Drugs
基金
国家自然科学基金资助项目(31270008
30570174
30900118
31070295
31100244
30710103092)
山西省国际科技合作(2010081070
2008081043)
关键词
代谢组学
中药材
道地药材
聚类
质量评价
metabolomics
traditional Chinese medicinal materials
genuine medicinal materials
cluster
quality evaluation
