摘要
目的探讨丙泊酚联用氟比洛芬酯镇痛在减轻人流术后子宫收缩痛中的应用效果。方法按入院的先后顺序,100例ASAⅠ～Ⅱ级需行人流的患者被随机分成观察组与对照组各50例。观察组经静脉先给予氟比洛芬酯50mg,对照组先给予生理盐水50ml,10min后两组均给予丙泊酚2.5mg/kg,静注丙泊酚速率200mg/min。评价两组在术前、术时的HR、BP和SPO2变化、麻醉效果及VAS评分等指标。结果术前及术时的SBP、DBP、HR、SpO2,组间差异均无统计学意义(P>0.05),而各组术时较术前均有下降,组间差异有统计学意义(P<0.05);麻醉效果,组间差异无统计学意义(P>0.05);观察组的苏醒即刻、15min、30min的VAS评分均低于对照组,组间差异无统计学意义(P>0.05)。结论丙泊酚联用氟比洛芬酯镇痛能有效减轻人流术后子宫收缩疼痛。
Objective To explore the clinical application of propofol associated flurbiprofen axetil analgesia in reducing the flow after uterine contraction pain. Methods According to the order of admission, 100 ASA Ⅰ～Ⅱ cases requires to line abortion were randomly divided into observation group and control group （n= 50）. Observation group was first given intravenous flurbiprofen axetil 50 mg, while the control group received saline 50 ml; After 10 min, the two groups were given propofol 2.5 mg/kg, intravenous propofol rate 200 mg/min. Records were evaluated preoperatively, surgery when HR, BP and SPO2 changes, anesthetic effects and VAS score indicators. Results Preoperative and intraoperative SBP, DBP, HR, SPO2, the difference between the groups was not statistically significant （P〉0.05）, each group surgery when compared with preoperative decreased in the difference between the groups was statistically significant （P〈0. 05）; anesthetic effect, the difference between the groups was not statistically significant （P〉0. 05）; observation group wake up instantly, 15min, 30min VAS scores were lower than the control group, the difference between the two groups was not statistically significant （P〉O. 05）. Conclusion Propofol combined with flurbiprofen axetil the analgesic can effectively reduce uterine cramping after abortion.
出处
《西部医学》
2013年第4期542-543,548,共3页
Medical Journal of West China
关键词
氟比洛芬酯
丙泊酚
人流
镇痛
子宫
收缩痛
Flurbiprofen axetil
Propofol
Crowd
Analgesia
Uterus
Contraction pain
