摘要
[摘要] 目的 探讨丙型肝炎病毒感染（HCV）与非霍奇金淋巴瘤（NHL）发病的相关性。方法：对2007年10月-2012年10月河南省肿瘤医院收治的208例NHL患者的HCV感染状况进行了研究，并以同时期年龄、性别等因素进行配对的白血病患者、其它肿瘤患者以及健康体检者分别作为三组对照，Elisa法检测抗-HCV抗体来得出4组人群中HCV感染情况。结果：NHL患者外周血中抗-HCV抗体阳性率（24/208,11.5%）显著高于白血病组（8/208,3.8%）（Χ^28.667, P=0.003）、其它肿瘤组（6/208,2.9%）（Χ^211.639, P=0.001）以及健康体检组（2/208,1.0%）（Χ^219.856, P=0.000）。结论：提示本地区NHL的发病与HCV感染存在一定的相关性。
[Abstract] Objective To explore the relation of non-hodgkin lymphoma（NHL） and HCV infection. Methods We investigated the HCV infection of 208 non-hodgkin lymphoma patients in Henan Tumor Hospital from October 2007 to October 2012, and leukemia patients, other tumor patients and healthy people which were paired with age and gender were used as control groups. Then Elisa method was used to detected the HCV-antibody in serum. Results HCV-antibody positive rate in NHL patients（24/208,11.5%）was significantly higher than leukemia patienta（8/208,3.8%）（Χ^28.667, P=0.003）,other tumor patients（6/208,2.9%）（Χ^211.639, P=0.001） and healthy people（2/208,1.0%）（Χ^219.856, P=0.000）. Conclusion HCV infection is related to NHL in this area.
出处
《白血病．淋巴瘤》
CAS
2013年第3期151-153,共3页
Journal of Leukemia & Lymphoma
基金
国家自然科学基金（81000921）
