摘要
目的研究淋巴细胞恶性增生性疾病(MLPD)患者乙型(HBV)、丙型(HCV)肝炎病毒感染情况。方法回顾性分析67例初诊MLPD和170例正常体检人群血清乙型肝炎病毒标记物和抗HCV。结果67例MLPD中HBV阳性10例(14.93%)。其中33例淋巴瘤(NHL/HD)中6例阳性,16例MM中2例阳性,18例淋巴细胞白血病(ALL/CLL)中2例阳性,170例体检人员中8例阳性(4.71%),MLPD患者群体内HBV感染的阳性率高于正常人群的HBV感染的阳性率(P<0.01);67例MLPD中抗HCV阳性5例(7.46%),其中33例淋巴瘤中2例阳性,16例MM中2例阳性,18例淋巴细胞白血病中l例阳性,170例体检人员中2例阳性(1.18%)。MLPD患者群体内抗HCV的阳性率高于正常人群抗HCV的阳性率(P<0.05)。结论MLPD患者有较高的HBV和HCV感染率。
Objectives To Study the hepatitis B virus（HBV） and hepatitis c virus （HCV） infection in malignant lymphocytic proliferation disease（MLPD）. Methods To chose 67 previously untreated patients with MLPD as study objects, The normal controls consisted of 170 heathy peoples. The markers of HBV and anti-hepatitis C virus antibody（anti-HCV） were detected in two groups, respectively. Results Ten of 67 （14.93 %） eases with MLPD have HBV infection. Six of 33 eases with NHL/HD, two of 16 ease with MM, two of 18 ease with ALL/CLL and eight of 170（4.71%） normal population have HBV infection, the infection rate of HBV in MALD patients is statistically higher than in the control group（P 〈0.01）; Five of 67（7.46 %） eases with MLPD have positive anti-HCV, two of 33 eases with NHL/HD, two of 16 ease with MM, one of 18 ease with ALL/CLL and two of 170（1.18 %） normal population have positive anti-HCV, the infection rate of HCV in MALD patients is statistically higher than in the control group（P 〈0.05）. Conclusion The prevalence of HBV and HCV infection is higher in MLPD patients than general population.
出处
《白血病．淋巴瘤》
CAS
2005年第5期299-301,共3页
Journal of Leukemia & Lymphoma
关键词
淋巴细胞恶性增生疾病
肝炎病毒
感染
Malignant lymphocytic proliferation disease
Hepatitis virus infection
