摘要
目的探讨128层螺旋CT低剂量高分辨扫描技术在肺间质病变观察中的临床价值。方法 92例引起肺间质病变的结缔组织疾病患者,采用A剂量(管电压140kV,管电流250mAs)、B剂量(管电压140kV,管电流150mAs)和C剂量(管电压140kV,管电流75mAs)分别对感兴趣区进行高分辨CT扫描;探测器宽度10mm,层厚0.625mm轴扫;病变观察指标包括磨玻璃病变、小叶间隔、小叶内隔、支气管血管束、胸膜下线、网状影、蜂窝状影、小结节。通过卡方检验分析低剂量高分辨CT扫描总体病变指标和单项病变指标的显出率。结果①A剂量与B剂量总体病变指标进行两两比较,差异性无统计学意义(P>0.025);A剂量与C剂量比较差异有统计学意义(P<0.025)。另A剂量与B剂量单项病变指标之间进行比较差异无统计学意义(P>0.025);②A剂量与B剂量、C剂量分别进行单项病变指标比较,显示无差异(P>0.025),尤其是增厚支气管血管束、网格状影和小结节在三种剂量无明显差异;区别略明显的是磨玻璃病变、胸膜下线和增厚小叶内隔,以C剂量显出率最低。结论本研究表明低剂量高分辨CT扫描(140kV,150mAs)在肺间质病变的观察诊断中是可行的,可以降低患者40%的辐射量,可实现肺高分辨CT扫描的同时降低患者的辐射剂量。
Objective To investigate the value on clinical observation implemented with 128 layer spiral CT low dose high-resolution scanning technology in pulmonary interstitial lesions. Methods 92 cases of interstitial lung disease caused by the connective tissue disease, to be applied with A dose （tube voltage 140 kV, tube current 250 mAs）, B dose （tube voltage 140 kV, tube current 150 mAs） and C dose （tube voltage 140 kV, tube current 75 mAs） respectively, to be irnple- mented with highresolution CT scanning for the interested region. With probe width 10 ram, slice thickness 0. 625 mm, axis scanning; Observation indexes on lesions including ground-glass lesion, interlobular septa, Intralobular septa, bronchial blood vessel bundle, pleural line, reticular shadow, honeycomb shadow and small nodules. Analysis displays the show rates of overall disease index and single disease index with low dose high-resolution CT scanning by the chi-square test. Results ① Comparison of the overall disease indexes on A dose group with B dose group reveals no statistical significance （ P 〉0. 025） ; Comparison of the overall disease indexes on A dose group with C dose group reveals no statistical significance （ P 〈0. 025） ; and moreover comparison of the single disease indexes on A dose group with B dose group reveals no statistical significance （ P 〉0. 025） ; ② Comparison of the single disease indexes among A dose group, B dose group and C dose group reveals no statistical significance （ P 〉0. 025）. Conclusion The study shows it＇s feasible to implement low dose high-resolution CT scanning for the observation diagnosis of pulmonary interstitial lesions by decreasing 40%radiation level on patients, and achieves high-resolution CT scanning for pulmonary detection by decreasing radiation level on patients simultaneously.
出处
《医学影像学杂志》
2013年第3期408-411,共4页
Journal of Medical Imaging
基金
2010年河北省科学技术研究与发展计划项目
项目编号102761123
关键词
低剂量
辐射
高分辨
体层摄影术
X线计算机
肺间质病变
Low dose
Radiation
High-resolution, X-line computer
Pulmonary interstitial lesions
