摘要
目的通过电子胃镜及快速尿素酶试验对胃食管反流病患者进行检查,探讨阜阳地区食管黏膜糜烂型胃食管反流病(GERD)、非食管黏膜糜烂型胃食管反流病(NERD)与幽门螺杆菌(HP)感染的关系,为胃食管反流病患者临床治疗提供新的方法与思路。方法收集阜阳市人民医院2009年1月-2011年12月门诊及住院部确诊为胃食管反流病的患者210例,其中HP感染组135人,非HP感染组75人。两组患者均进行电子胃镜分级和快速尿素酶试验。结果阜阳地区胃食管反流患者HP感染组食管黏膜糜烂占总数的百分比为82%,非糜烂性食管炎占总数18%。非HP感染组食管糜烂占总数的74%,非糜烂性食管炎占总数26%,HP感染组食管黏膜糜烂发生率高于非HP感染组,P<0.05,差异有统计学意义。总发病人数中HP感染组占总发病比例64%,非HP感染组占总发病比例36%。两者比较差异有统计学意义(P<0.05)。结论阜阳地区胃食管反流病发病率及胃食管反流病患者食管黏膜糜烂发病比例与HP感染有明显的相关性。
Objective To study the correlation of Gastroesophageal reflux disease（GERD） and non-erosive reflux disease（NERD） with HP infection,and explore a new method and idea for the treatment of GERD.Methods Collect 210 patients that diagnosed as GERD our hospital Outpatient service and be in hospital patients in our hospital during January 2009 to January 2011,the one group with HP infection 135 cases,the other group with no HP infection 75 cases.Two groups of patients were performed endoscopic classification and rapid urease test.Results The morbidity proportion of the GERD＇s is 82% and NERD＇s is 18% in the group with HP infection.The morbidity proportion of the GERD＇s is 74% and NERD＇s is 26% in the group with with no HP infection.The comparisons of two groups have Significant statistical differences（P0.05）.Conclusion The morbidity proportion and mucosal erosion of GERD is significant correlation with HP infection in fu yang district.
出处
《中华全科医学》
2013年第3期401-402,共2页
Chinese Journal of General Practice
关键词
胃食管反流病
胃镜分级
快速尿素酶试验
Gastroesophageal reflux disease
Endoscopic classification
Rapid urease test
