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左旋甲状腺素抑制性疗法治疗甲状腺良性结节的临床研究 被引量:8

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摘要 【目的】探讨左旋甲状腺素(L—T。)抑制性疗法治疗甲状腺良性结节的临床疗效。【方法】对92例甲状腺良性结节患者中的50例为治疗组,给予卜Tt治疗1年;对照组42例,不予任何药物治疗,仅临床随访观察,每3个月超声测量两组甲状腺结节大小变化并检测甲状腺素水平,均随访12个月。【结果】经L—T。治疗后,患者未见严重不良反应,最大结节横截面直径由治疗前的(65.67±10.38)mm降低为(45.76±8.45)mm,与对照组的(63.25±9.47)mm相比差异有显著性(P〈0.05);甲状腺结节平均体积也由治疗前的(13.05±0.92)cm。降低为(10.11土0.82)cm3,与对照组的(12.45±0.89)cm3相比差异有显著性(P〈0.05)。【结论】L-T4抑制性疗法能有效安全地治疗良性甲状腺结节。
作者 徐鹏飞
出处 《医学临床研究》 CAS 2013年第2期374-376,共3页 Journal of Clinical Research
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