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宫腔置米索预防剖宫产后出血的临床研究

Clinical Study on Reduction of Postpartum Bleeding in Cesarean Operation by Misoprostol
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摘要 目的 :探寻安全、方便、快速、可靠的预防剖宫产产后 2小时 (第四产程 )出血的方法 ,本研究观察米索前列醇宫腔放置预防剖宫产第四产程产后出血的效果。方法 :选择 36 6例剖宫产病例 ,随机分为米索前列醇 +催产素组 (简称米索组 )和催产素组 ,米索组 132例 ;胎儿娩出后宫体注射催产素 2 0U ,胎盘、胎膜娩出后宫腔放置米索 2 0 0 μg ;催产素组 2 34例 ;胎儿娩出后宫体注射催产素 2 0U ,再静脉滴注催产素 2 0U ,以上两组观察第四产程的出血量。结果 :第四产程平均出血量 :米索组为 (80 .1± 31.3)ml,催产素组为 (14 0± 80 .7)ml ,两组比较差异性极显著 (P <0 .0 1)。结论 :米索前列醇能较好地预防剖宫产术后第四产程的出血 ,且用药安全、方便、快速。 Objective:To search for the safe、convenient、quick and secure approach of reducing postpartum bleeding within 2 hours after cesarean operation(fourth stage of labor).The research depended on observing the effects of misoprostol that was placed in uterine cavity to reduce postpartum bleeding in cesarean operation of the fourth stage of labor.Methods:366 cesarean sections were randomized into two groups:In misoprostol group ( n =132):20U oxytocin was injected into the uterines muscles immediately after the delivery of the baby and 200μg misoprostol was placed in uterine cavity immediately after the delivery of the placenta and fetal membranes;In oxytocin group( n =234):20U oxytocin was injected into uterine muscles and 20U intravenous injection immediately after the delivery of the baby.The amount of bleeding within 2 hours after the delivery was measured.Results:The amount of bleeding in misoprostol group was (80.1±31.3)ml.(140±80.7)ml in oxytocin group respectively.The difference was significant( P <0.01)between the misoprostol group and oxytocin group.Conclusion:Misoprostol is more effective,safer,more convenient,quicker and more secure in reduction of postpartum bleeding of the fourth stage of labor.
出处 《镇江医学院学报》 2000年第3期440-441,共2页 Journal of Zhenjiang Medical College
关键词 剖宫产术 第四产程 产后出血 米索前列醇 催产素 Cesarean operation(section) Misoprostol Fourth stage of labor Postpartum hemorrhage Oxytocin
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