摘要
目的 探讨纤维蛋白降解产物 (FDP)、D 二聚体 (D dimer)等指标用于矽肺早期诊断的意义和价值。方法 对无矽肺 0 + 者 ,Ⅰ期矽肺患者进行六项指标的测定。结果 经方差分析 ,0 + 组中铜蓝蛋白 (CP)、血清羟脯氨酸(HYP)、丙二醛 (MDA)、超氧化物歧化酶 (SOD)及FDP均高于正常对照组 ,Ⅰ期组的CP、MDA、HYP、D dimer水平均高于0 + 组。判别分析表明 ,CP、MDA、HYP、D dimer四项指标建立的判别方程与矽肺Ⅰ期X线诊断符合率为 10 0 % ,0 + 为74 1%。结论 D dimer、CP、MDA、HYP可作为矽肺早期诊断的指标。
Objective To explore the significance and value of fibrin degradation products (FDP), D dimer and other biochemical indexes used in early diagnosis of silicosis.Methods Six biochemical indexes were detected in 0 + and I stage.Results ANOVA indicated that the levels of five indexes (CP, MDA, HYP, SOD, FDP) in 0 + are higher than those of control group except D dimer, the levels of CP, MDA, HYP, D dimer in Ⅰ stage were higher than those of 0 +. Discriminant equations set by D dimer, CP, MDA and HYP were used in diagnosis of silicosis and the rate of accuracy in stage Ⅰ was shown to be 100% and that in 0 + to be 74 1%.Conclusion D dimer, CP, MDA, HYP could be used in early diagnosis of silicosis.
出处
《中国职业医学》
CAS
2000年第5期19-20,共2页
China Occupational Medicine
基金
广西壮族自治区科技厅青年基金项目!(桂科青 9731 0 1 0 )
关键词
纤维蛋白降解产物
D-二聚体
早期诊断
矽肺
Fibrin degradation product(FDP), D dimer, early diagnosis, silicosis
